SCHEMBL15445894

SCHEMBL15445894

CCOC(=O)c1cccc(Cc2cn(S(=O)(=O)c3ccccc3)c3ccccc23)c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 1/20 0.54
HTR6 P50406 12/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
HTR1A P08908 1/20 0.47
DRD2 P14416 1/20 0.47
HTR1D P28221 1/20 0.47
HTR1B P28222 1/20 0.47
HTR1F P30939 1/20 0.47
HTR7 P34969 1/20 0.47
DRD3 P35462 1/20 0.47
PLK1 P53350 1/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TNF P01375 1/20 0.45
CA2 P00918 1/20 0.44
CYP4F2 P78329 1/20 0.43
CYP4A11 Q02928 1/20 0.43
F2RL3 Q96RI0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15445888 0.78 HTR6 (0.56) ALKHTR6HTR1ADRD2HTR1D
SCHEMBL15445918 0.76 HTR6 (0.63) HTR6MEN1KMT2ADRD2HTR7
SCHEMBL27746995 0.72 KMT2A (0.53) HTR6MEN1KMT2APLK1LMNA
SCHEMBL946691 0.71 HTR6 (0.75) HTR6HTR1ADRD2HTR1DHTR1B
SCHEMBL30689018 0.71 MEN1 (0.64) ALKHTR6MEN1KMT2APLK1
SCHEMBL6089520 0.71 MEN1 (0.64) ALKHTR6MEN1KMT2APLK1
SCHEMBL1513257 0.71 L3MBTL1 (0.45) ALKKMT2ALMNACA2
SCHEMBL28471054 0.70 ALK (1.00) ALKHTR6HTR1ADRD2HTR1D
SCHEMBL16704081 0.70 HTR6 (0.69) HTR6MEN1KMT2AHTR1ADRD2
SCHEMBL28465462 0.70 ALK (0.76) ALKHTR6HTR1ADRD2HTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9273070-B2 Organozinc complexes and processes for making and using the same KNOCHEL PAUL (DE) 2016-03-01 US disclosed
US-9273070-B2 Organozinc complexes and processes for making and using the same KNOCHEL PAUL (DE) 2016-03-01 US disclosed
US-20140031545-A1 ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME LUDWIG-MAXIMILIAN-UNIVERSITAT MUNCHEN (DE) 2014-01-30 US disclosed
US-20140031545-A1 ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME LUDWIG-MAXIMILIAN-UNIVERSITAT MUNCHEN (DE) 2014-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140031545-A1 ORGANOZINC COMPLEXES AND PROCESSES FOR MAKING AND USING THE SAME ODC1, AOC1, ADH1C ALK 1085/4885HTR6 3332/4885MEN1 673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.