SCHEMBL15447647

SCHEMBL15447647

CC(C)(C)n1c2ccccc2c2ccc3c4ccccc4n(-c4ccccc4)c3c21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ATM Q13315 1/20 0.53
MAPK8 P45983 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 1/20 0.38
GLA P06280 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
HPGD P15428 1/20 0.38
CYP2C19 P33261 1/20 0.38
PGR P06401 3/20 0.37
MAPK9 P45984 1/20 0.37
PLA2G2A P14555 1/20 0.36
IL1R1 P14778 1/20 0.35
RECQL P46063 1/20 0.35
GPR3 P46089 1/20 0.34
MAPK1 P28482 2/20 0.34
ALKBH5 Q6P6C2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17827623 0.86 GPR3 (0.44) KDM4EL3MBTL1ATMKMT2AALDH1A1
SCHEMBL16231019 0.85 KDM4E (0.51) KDM4EL3MBTL1ATMMAPK8KMT2A
SCHEMBL15447734 0.85 KDM4E (0.47) KDM4EL3MBTL1ATMMAPK8KMT2A
SCHEMBL30286748 0.84 L3MBTL1 (0.74) KDM4EL3MBTL1ATMMAPK8KMT2A
SCHEMBL127119 0.84 L3MBTL1 (0.74) KDM4EL3MBTL1ATMMAPK8KMT2A
SCHEMBL126314 0.82 L3MBTL1 (0.71) KDM4EL3MBTL1ATMMAPK8KMT2A
SCHEMBL24703373 0.81 KDM4E (0.64) KDM4EL3MBTL1ATMMAPK8KMT2A
SCHEMBL10027546 0.81 L3MBTL1 (0.75) KDM4EL3MBTL1ATMMAPK8KMT2A
SCHEMBL15447656 0.81 KDM4E (0.53) KDM4EL3MBTL1ATMMAPK8KMT2A
SCHEMBL10206243 0.81 KDM4E (0.53) KDM4EL3MBTL1ATMMAPK8KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225205-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-13 US disclosed
US-20230225205-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-07-13 US disclosed
US-20230014761-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-19 US disclosed
US-20220393118-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF CHE, CHI MING (CN) 2022-12-08 US disclosed
US-20210066616-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-03-04 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9997712-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-9960357-B2 Spiro-type compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2018-05-01 US disclosed
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2017-12-21 US disclosed
US-9324949-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-26 US disclosed
US-9318710-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-04-19 US disclosed
US-20160028016-A1 BORON-NITROGEN POLYAROMATIC COMPOUNDS AND THEIR USE IN OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-20150021555-A1 DONOR-ACCEPTOR COMPOUNDS WITH NITROGEN CONTAINING HETEROPOLYAROMATICS AS THE ELECTRON ACCEPTOR UNIVERSAL DISPLAY CORPORATION 2015-01-22 US disclosed
US-8927749-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-06 US disclosed
US-20140332758-A1 DONOR-ACCEPTOR COMPOUNDS WITH NITROGEN CONTAINING POLYAROMATICS AS THE ACCEPTOR UNIVERSAL DISPLAY CORPORATION (US) 2014-11-13 US disclosed
US-20140291638-A1 HOST MATERIALS FOR OLED APPLICATION UNIVERSAL DISPLAY CORPORATION (US) 2014-10-02 US disclosed
US-20140252318-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-09-11 US disclosed
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence UNIVERSAL DISPLAY CORPORATION (US) 2014-05-29 US disclosed
US-20140027734-A1 BORON-NITROGEN POLYAROMATIC COMPOUNDS AND THEIR USE IN OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2014-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230014761-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 KDM4E 2849/4885L3MBTL1 1282/4885ATM 4660/4885
US-20140145149-A1 Organic Luminescent Compound With Delayed Fluorescence OCIAD1, OCIAD2, MLYCD KDM4E 3261/4885L3MBTL1 303/4885ATM 2395/4885
US-20230225205-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP KDM4E 4316/4885L3MBTL1 1490/4885ATM 3621/4885
US-20210066616-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP KDM4E 4316/4885L3MBTL1 1490/4885ATM 3621/4885
US-20220393118-A1 TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF PDCD2L, TTL, TTLL12 KDM4E 1731/4885L3MBTL1 396/4885ATM 1650/4885
US-20170365787-A1 SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME CRY1, NR2E3, LEF1 KDM4E 3359/4885L3MBTL1 3362/4885ATM 1650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.