SCHEMBL658276

SCHEMBL658276

CCCC[Sn](CCCC)(CCCC)c1ccncc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.41
CYP3A4 P08684 2/20 0.41
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
POLB P06746 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
NAAA Q02083 1/20 0.36
LMNA P02545 7/20 0.34
NPC1 O15118 4/20 0.34
TSHR P16473 2/20 0.34
RAB9A P51151 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 5/20 0.33
HTT P42858 2/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9742279 0.92 NAAA (0.41) CYP2D6CYP3A4ALDH1A1MAPTPOLB
SCHEMBL29851305 0.91 CYP3A4 (0.36) CYP2D6CYP3A4ALDH1A1MAPTPOLB
SCHEMBL1983658 0.84 TSHR (0.32) CYP2D6MAPTLMNATSHRCYP1A2
SCHEMBL28275 0.78 LOXL2 (0.32) TDP1L3MBTL1
SCHEMBL15648671 0.77 BDKRB2 (0.36) CYP2D6CYP3A4ALDH1A1MAPTLMNA
SCHEMBL15648819 0.77 BDKRB2 (0.36) CYP2D6CYP3A4ALDH1A1MAPTLMNA
SCHEMBL276811 0.77 LTA4H (0.38) TSHRTDP1SMN1; SMN2NPSR1
SCHEMBL154603 0.76 L3MBTL1 (0.49) CYP2D6CYP3A4ALDH1A1POLBHDAC3
SCHEMBL29851135 0.76 L3MBTL1 (0.49) CYP2D6CYP3A4ALDH1A1POLBHDAC3
SCHEMBL1452840 0.76 HTT (0.38) CYP3A4ALDH1A1LMNANPC1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112209955-A Carborane violet essence derivative, metal supermolecule polymer thereof, synthetic method and application 西安交通大学 2021-01-12 CN claimed
CN-110872268-A Isocoumarin derivative and preparation method and medicinal application thereof 复旦大学 2020-03-10 CN claimed
US-12577225-B2 Nuclear transport modulators and uses thereof Karyopharm Therapeutics Inc. (US) 2026-03-17 US disclosed
EP-4688772-A1 BIARYL DERIVATIVES AND RELATED USES Moma Therapeutics, Inc. (US) 2026-02-11 EP disclosed
EP-4051667-B1 HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS LILAC THERAPEUTICS INC (US) 2026-01-28 EP disclosed
US-12528815-B2 5-amino-8-(4-pyridyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one compounds for use against cancer NXERA PHARMA UK LIMITED (GB) 2026-01-20 US disclosed
US-20260015360-A1 BIARYL DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2026-01-15 US disclosed
US-20260001886-A1 ENPP1 INHIBITORS I RE VENTURES I LLC (US) 2026-01-01 US disclosed
WO-2025233863-A1 ENPP1 INHIBITORS RE VENTURES I, LLC (US) 2025-11-13 WO disclosed
US-20250339541-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-11-06 US disclosed
US-20250213699-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-07-03 US disclosed
US-5488055-A ADMINISTERING GMP HOSPHODIESTERASE INHIBITORS FOR TREATMENT OF CONGESTIVE HEART FAILURE AND CARDIOVASCULAR DISORDERS SANOFI WINTHROP INC. (US) 1996-01-30 US disclosed
WO-1995034564-A1 PIRYDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-12-21 WO disclosed
WO-1995021838-A1 PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-08-17 WO disclosed
EP-0290591-B1 MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS MERCK PATENT GmbH (DE) 1991-03-13 EP disclosed
US-4959363-A HERPES VIRUS STERLING DRUG INC. (US) 1990-09-25 US disclosed
EP-0348497-A1 NON-LINEAR OPTICAL MATERIAL CONTAINING A HEMICYANINE COMPOUND AND PROCESS FOR PRODUCING IT MERCK PATENT GmbH (DE) 1990-01-03 EP disclosed
WO-1989005843-A1 NON-LINEAR OPTICAL MATERIAL CONTAINING A HEMICYANINE COMPOUND AND PROCESS FOR PRODUCING IT MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-06-29 WO disclosed
EP-0290591-A1 MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS. MERCK PATENT GMBH (DE) 1988-11-17 EP disclosed
WO-1988004305-A1 MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339541-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS ASGR1, ENGASE, FCGR2A CYP2D6 4501/4885CYP3A4 4537/4885ALDH1A1 3319/4885
US-20260015360-A1 BIARYL DERIVATIVES AND RELATED USES POLB, POLA1, POLN CYP2D6 47/4885CYP3A4 448/4885ALDH1A1 824/4885
US-20250213699-A1 ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS ASGR1, ENGASE, FCGR2A CYP2D6 4501/4885CYP3A4 4537/4885ALDH1A1 3319/4885
US-12577225-B2 Nuclear transport modulators and uses thereof XPO1, XPOT, CSE1L CYP2D6 1343/4885CYP3A4 1846/4885ALDH1A1 3320/4885
US-20260001886-A1 ENPP1 INHIBITORS I ENPP1, ENPP2, ENPP3 CYP2D6 2471/4885CYP3A4 4457/4885ALDH1A1 2998/4885
US-12528815-B2 5-amino-8-(4-pyridyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3-one compounds for use against cancer ADORA1, ADORA3, OPRL1 CYP2D6 923/4885CYP3A4 1868/4885ALDH1A1 692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.