Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491166 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CYP3A4CYP1A1CYP1B1CA1 | |
| SCHEMBL11359739 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP1A1CYP1B1CA1 | |
| SCHEMBL697263 | 0.78 | ABL1 (0.57) | ALDH1A1CYP3A4CYP1A1CYP1B1CA1 | |
| SCHEMBL18795416 | 0.77 | ERN1 (0.43) | ALDH1A1CYP3A4CYP1A1CYP1B1CYP2A6 | |
| 1,3,5-Trimethoxybenzene SCHEMBL28493 | 0.75 | ALDH1A1 (1.00) | ALDH1A1CYP3A4CYP1A1CYP1B1CA1 | |
| SCHEMBL699056 | 0.73 | CYP3A4 (0.64) | ALDH1A1CYP3A4CYP1A1CYP1B1CA1 | |
| SCHEMBL19724 | 0.73 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CYP1A1CYP1B1CA1 | |
| SCHEMBL1636165 | 0.73 | NQO1 (0.48) | ALDH1A1CYP3A4CA1CA2CA12 | |
| SCHEMBL1637762 | 0.73 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8408115 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230016405-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | THE UNIVERSITY OF TOKYO (JP) | 2023-01-19 | — | — | US | claimed |
| EP-4116286-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | The University of Tokyo (JP) | 2023-01-11 | — | — | EP | claimed |
| CN-115175889-A | Process for producing fluorine-containing olefin | 国立大学法人东京大学 | 2022-10-11 | — | — | CN | claimed |
| EP-3740493-B1 | INHIBTEURS DE L'INDOLEAMINE 2,3-DIOXYGÉNASE ET/OU DU TRYPTOPHANE DIOXYGÉNASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-12-01 | — | — | EP | claimed |
| WO-2021067374-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION (US) | 2021-04-08 | — | — | WO | claimed |
| US-20210094935-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION | 2021-04-01 | — | — | US | claimed |
| US-20200405696-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-12-31 | — | — | US | claimed |
| EP-3740493-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | Idorsia Pharmaceuticals Ltd (CH) | 2020-11-25 | — | — | EP | claimed |
| CN-111601810-A | Inhibitors of indoleamine 2, 3-dioxygenase and/or tryptophan 2, 3-dioxygenase | 爱杜西亚药品有限公司 | 2020-08-28 | — | — | CN | claimed |
| EP-2857388-A1 | Azoles containing sulfone | Grünenthal GmbH (DE) | 2015-04-08 | — | — | EP | claimed |
| US-20080312231-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-12-18 | — | — | US | claimed |
| WO-2008131947-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-11-06 | — | — | WO | claimed |
| US-20080249128-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2008-10-09 | — | — | US | claimed |
| WO-2008046573-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES FOR USE AS BRADYKININ 1 RECEPTOR MODULATORS | Grünenthal GmbH (DE) | 2008-04-24 | — | — | WO | claimed |
| JP-2002514252-A | — | — | 2002-05-14 | — | — | JP | claimed |
| US-6103658-A | Olefin polymerization catalysts containing group 8-10 transition metals, processes employing such catalysts and polymers obtained therefrom | EASTMAN CHEMICAL COMPANY (US) | 2000-08-15 | — | — | US | claimed |
| EP-0973762-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS , PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2000-01-26 | — | — | EP | claimed |
| US-5821024-A | POLYESTER BINDER OF A DICARBOXYLIC ACID AND A POLYOL BLEND OF ETHERIFIED DIPHENOLS | EASTMAN KODAK COMPANY (US) | 1998-10-13 | — | — | US | claimed |
| WO-1998040374-A2 | OLEFIN POLYMERIZATION CATALYSTS CONTAINING GROUP 8-10 TRANSITION METALS, BIDENTATE LIGANDS, PROCESSES EMPLOYING SUCH CATALYSTS AND POLYMERS OBTAINED THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 1998-09-17 | — | — | WO | claimed |
| US-4692529-A | Method for synthesizing a magenta coupler by selectively etherifying 4-hydroxy-5-pyrazolone | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1987-09-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249128-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, NPSR1 | ALDH1A1 2737/4885CYP3A4 2431/4885CYP1A1 1341/4885 |
| US-20080312231-A1 | Substituted Sulfonamide Compounds | SULT2A1, SULT1A1, SCN1A | ALDH1A1 511/4885CYP3A4 351/4885CYP1A1 384/4885 |
| US-20230016405-A1 | METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN | CYP2F1, CYP4F2, POF1B | ALDH1A1 845/4885CYP3A4 119/4885CYP1A1 34/4885 |
| US-20200405696-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN 2,3-DIOXYGENASE | IDO2, TDO2, IDO1 | ALDH1A1 631/4885CYP3A4 255/4885CYP1A1 254/4885 |
| US-20210094935-A1 | BICYCLIC HETEROCYCLES AS FGFR INHIBITORS | FGFR3, FGFR1, FGFR2 | ALDH1A1 802/4885CYP3A4 936/4885CYP1A1 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.