Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12440430 | 0.78 | HTR3E (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL14648359 | 0.74 | MAPK1 (0.32) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13091319 | 0.72 | CES2 (0.36) | — | |
| SCHEMBL22316707 | 0.70 | TDO2 (0.36) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7931082 | 0.69 | MAPK1 (0.57) | — | |
| SCHEMBL12440721 | 0.68 | HTR3E (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3682577 | 0.67 | ALDH1A1 (0.53) | — | |
| SCHEMBL7549121 | 0.67 | CA12 (0.35) | — | |
| SCHEMBL10153372 | 0.66 | KMT2A (0.32) | — | |
| SCHEMBL8528070 | 0.64 | CYP3A4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2567698-B1 | GPR 17 agonists and screening assay | UNIV BONN (DE) | 2014-02-12 | — | — | EP | disclosed |