SCHEMBL15469073

SCHEMBL15469073

CN1c2ccccc2C=Cc2cc(CC(C)(C)C)c3ccccc3c21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
MAPT P10636 4/20 0.35
NPSR1 Q6W5P4 3/20 0.35
LMNA P02545 2/20 0.35
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 5/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
MAPK1 P28482 3/20 0.34
BLM P54132 3/20 0.34
KDM4E B2RXH2 2/20 0.34
POLB P06746 2/20 0.34
HTT P42858 2/20 0.34
RECQL P46063 2/20 0.34
NSD2 O96028 1/20 0.34
RAD52 P43351 1/20 0.34
MMP14 P50281 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
P2RX4 Q99571 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10133835 0.72 P2RX4 (0.35) MEN1KMT2AMAPTNPSR1LMNA
SCHEMBL12793388 0.69 MEN1 (0.40) MEN1KMT2AMAPTNPSR1LMNA
SCHEMBL12793374 0.68 P2RX4 (0.43) MEN1KMT2AMAPTNPSR1LMNA
SCHEMBL2607158 0.67 MAPT (0.49) MEN1KMT2AMAPTNPSR1LMNA
SCHEMBL27690109 0.66 RIPK1 (0.39) MEN1KMT2AMAPTLMNAL3MBTL1
SCHEMBL19885348 0.62 MAPT (0.44) MEN1KMT2AMAPTNPSR1LMNA
SCHEMBL12841613 0.62 MEN1 (0.44) MEN1KMT2AMAPTNPSR1LMNA
SCHEMBL15469131 0.62 NR1H3 (0.46) MEN1KMT2AMAPTNPSR1LMNA
SCHEMBL8109589 0.61 MTNR1A (0.45) MEN1KMT2AMAPTNPSR1LMNA
SCHEMBL2325159 0.61 MAOA (0.41) MEN1KMT2AMAPTMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20140042411-A1 METHOD FOR PURIFYING ORGANIC MATERIAL, MATERIAL FOR ORGANIC ELECTRONICS, PHOTOELECTRIC CONVERSION DEVICE, OPTICAL SENSOR, IMAGING DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2014-02-13 US disclosed