Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Creatine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MVD | P53602 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 14/20 | 0.36 |
| ▸ | CA2 | P00918 | 14/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Creatine SCHEMBL2817384 | 1.00 | MVD (0.42) | MVDNOS3NOS1NOS2CA1 | |
| Creatine SCHEMBL28000876 | 1.00 | MVD (0.42) | MVDNOS3NOS1NOS2CA1 | |
| Creatine SCHEMBL10710660 | 1.00 | MVD (0.42) | MVDNOS3NOS1NOS2CA1 | |
| Creatine SCHEMBL4966668 | 1.00 | MVD (0.42) | MVDNOS3NOS1NOS2CA1 | |
| Creatine SCHEMBL4110519 | 1.00 | MVD (0.42) | MVDNOS3NOS1NOS2CA1 | |
| Creatine SCHEMBL27189 | 1.00 | MVD (0.42) | MVDNOS3NOS1NOS2CA1 | |
| Creatine SCHEMBL21693685 | 0.98 | MVD (0.41) | MVDNOS3NOS1NOS2CA1 | |
| Creatine SCHEMBL21632997 | 0.98 | MVD (0.41) | MVDNOS3NOS1NOS2CA1 | |
| Creatine SCHEMBL21693673 | 0.98 | MVD (0.41) | MVDNOS3NOS1NOS2CA1 | |
| Creatine SCHEMBL21693688 | 0.98 | MVD (0.45) | MVDNOS3NOS1NOS2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4744580-A2 | COACHING BASED ON MENSTRUAL CYCLE | Whoop, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| EP-4736759-A2 | APPLIED DATA QUALITY METRICS FOR PHYSIOLOGICAL MEASUREMENTS | Whoop, Inc. (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4278361-B1 | COACHING BASED ON MENSTRUAL CYCLE | WHOOP INC (US) | 2026-04-15 | — | — | EP | disclosed |
| US-12575786-B2 | Detecting sleep intention | WHOOP, INC. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20260060615-A1 | WIRELESS BATTERY FOR PHYSIOLOGICAL MONITORING SYSTEM | WHOOP INC (US) | 2026-03-05 | — | — | US | disclosed |
| EP-3687392-B1 | APPLIED DATA QUALITY METRICS FOR PHYSIOLOGICAL MEASUREMENTS | WHOOP INC (US) | 2026-03-04 | — | — | EP | disclosed |
| US-20250380880-A1 | RECOMMENDATIONS BASED ON CONTINUOUS PHYSIOLOGICAL MONITORING | WHOOP INC (US) | 2025-12-18 | — | — | US | disclosed |
| US-12484850-B2 | Wireless battery for physiological monitoring system | WHOOP, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| US-20250331774-A1 | ADJUSTABLE STRAP FOR WEARABLE MONITOR | WHOOP INC (US) | 2025-10-30 | — | — | US | disclosed |
| US-20250288255-A1 | DETERMINING SLEEP NEED FROM PHYSIOLOGICAL MEASUREMENTS | WHOOP, INC. | 2025-09-18 | — | — | US | disclosed |
| US-20150251074-A1 | AUTOMATED EXERCISE RECOMMENDATIONS | WHOOP, INC. (US) | 2015-09-10 | — | — | US | disclosed |
| EP-2892421-A1 | SYSTEMS, DEVICES AND METHODS FOR CONTINUOUS HEART RATE MONITORING AND INTERPRETATION | Whoop, Inc. (US) | 2015-07-15 | — | — | EP | disclosed |
| US-20140350356-A1 | DETERMINING HEART RATE WITH REFLECTED LIGHT DATA | WHOOP INC. (US) | 2014-11-27 | — | — | US | disclosed |
| US-20140343372-A1 | AUTOMATIC LOCATION DETECTION OF A PHYSIOLOGICAL MEASUREMENT SYSTEM ON A USER'S BODY | WHOOP, INC. | 2014-11-20 | — | — | US | disclosed |
| US-20140323827-A1 | PHYSIOLOGICAL MEASUREMENT SYSTEM WITH A MULTI-CHIP MODULE | SILICON VALLEY BANK | 2014-10-30 | — | — | US | disclosed |
| US-20140323828-A1 | PHYSIOLOGICAL MEASUREMENT SYSTEM WITH MOTION SENSING | WHOOP, INC. | 2014-10-30 | — | — | US | disclosed |
| US-20140323880-A1 | DETERMINING A RECOVERY INDICATOR USING HEART RATE DATA | WHOOP, INC. | 2014-10-30 | — | — | US | disclosed |
| US-20140309542-A1 | DETERMINING CARDIOVASCULAR INTENSITY USING HEART RATE DATA | SILICON VALLEY BANK | 2014-10-16 | — | — | US | disclosed |
| WO-2014039567-A1 | SYSTEMS, DEVICES AND METHODS FOR CONTINUOUS HEART RATE MONITORING AND INTERPRETATION | BOBO ANALYTICS, INC. (US) | 2014-03-13 | — | — | WO | disclosed |
| US-20140073486-A1 | SYSTEMS, DEVICES AND METHODS FOR CONTINUOUS HEART RATE MONITORING AND INTERPRETATION | BOBO ANALYTICS, INC. (US) | 2014-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12575786-B2 | Detecting sleep intention | PER2, CHAT, HCRTR1 | MVD 3390/4885NOS3 2107/4885NOS1 2748/4885 |
| US-20260060615-A1 | WIRELESS BATTERY FOR PHYSIOLOGICAL MONITORING SYSTEM | FGF23, AXL, TRIB2 | MVD 4099/4885NOS3 1548/4885NOS1 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.