SCHEMBL155160

SCHEMBL155160

COC(=O)c1ccc(N)c(OC)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.62
ALDH1A1 P00352 6/20 0.61
KDM4E B2RXH2 5/20 0.61
HSD17B10 Q99714 3/20 0.61
HPGD P15428 3/20 0.61
GAA P10253 2/20 0.61
ATM Q13315 2/20 0.61
GLA P06280 1/20 0.61
CASP1 P29466 1/20 0.61
CASP7 P55210 1/20 0.61
KMT2A Q03164 2/20 0.55
USP2 O75604 1/20 0.55
LMNA P02545 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
HTT P42858 1/20 0.53
TSHR P16473 3/20 0.52
CYP3A4 P08684 3/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31265461 0.90 MAPT (0.54) MAPTALDH1A1KDM4EHSD17B10HPGD
SCHEMBL16392520 0.87 MAPT (0.57) MAPTALDH1A1KDM4EHPGDGAA
SCHEMBL25072701 0.86 ALDH1A1 (0.65) MAPTALDH1A1KDM4EHSD17B10HPGD
SCHEMBL30427425 0.85 ALDH1A1 (0.73) MAPTALDH1A1KDM4EHSD17B10HPGD
SCHEMBL51894 0.85 ALDH1A1 (0.73) MAPTALDH1A1KDM4EHSD17B10HPGD
SCHEMBL436813 0.85 ALDH1A1 (0.72) ALDH1A1HSD17B10GAAUSP2LMNA
Hydrochloric Acid SCHEMBL5065615 0.84 ALDH1A1 (0.71) MAPTALDH1A1KDM4EHSD17B10HPGD
SCHEMBL220432 0.83 LMNA (0.55) MAPTALDH1A1HSD17B10KMT2ALMNA
SCHEMBL1804675 0.83 MAPK1 (0.60) ALDH1A1HSD17B10GAAKMT2ALMNA
SCHEMBL8622568 0.83 ALDH1A1 (0.70) ALDH1A1HSD17B10HPGDGAAUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 837 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119837319-A Sustainable antibacterial deodorizing clothes and preparation method and application thereof 奥洁玛(北京)生物科技有限公司 2025-04-18 CN claimed
CN-118619922-A Hydroxamic acid compound, and preparation method and application thereof 郑州大学 2024-09-10 CN claimed
CN-122036587-A Zalutst compound and application thereof in inhibiting MLL1-WDR5 interaction 暨南大学 2026-05-15 CN disclosed
EP-4741386-A1 PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-13 EP disclosed
US-12612412-B2 Antiviral heterocyclic compounds ENANTA PHARMACEUTICALS, INC. (US) 2026-04-28 US disclosed
US-20260098032-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION PMV PHARMACEUTICALS INC (US) 2026-04-09 US disclosed
US-12569564-B2 Spirocyclic MDM2 modulator and uses thereof NEWAVE PHARMACEUTICAL INC. (US) 2026-03-10 US disclosed
EP-4688751-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS Enanta Pharmaceuticals, Inc. (US) 2026-02-11 EP disclosed
US-20260014261-A1 TARGETED PROTEIN MODIFICATION WEATHERWAX BIOTECHNOLOGIES CORP (US) 2026-01-15 US disclosed
EP-4676602-A1 COMPOUNDS TARGETING MUTATIONS IN P53 AND USES THEREOF Merck Sharp & Dohme LLC (US) 2026-01-14 EP disclosed
US-12509470-B2 Antiviral heterocyclic compounds ENANTA PHARMACEUTICALS, INC. (US) 2025-12-30 US disclosed
WO-1996022295-A9 TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS 1996-11-14 WO disclosed
WO-1996022293-A1 TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS AMERICAN CYANAMID COMPANY (US) 1996-07-25 WO disclosed
WO-1996022282-A1 TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS AMERICAN CYANAMID COMPANY (US) 1996-07-25 WO disclosed
WO-1996022295-A1 TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS AMERICAN CYANAMID COMPANY (US) 1996-07-25 WO disclosed
US-5536718-A Tricyclic benzazepine vasopressin antagonists AMERICAN CYANAMID COMPANY (US) 1996-07-16 US disclosed
US-5532235-A TO TREAT EXCESS RENAL REABSORPTION AMERICAN CYANAMID COMPANY (US) 1996-07-02 US disclosed
EP-0711768-A1 BENZIMIDAZOLE DERIVATIVE MITSUI TOATSU CHEMICALS, Inc. (JP) 1996-05-15 EP disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed
US-5356926-A Antiinflammatory agents WARNER-LAMBERT COMPANY (US) 1994-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509470-B2 Antiviral heterocyclic compounds NR3C1, ZC3HAV1, HAVCR2 MAPT 4847/4885ALDH1A1 3560/4885KDM4E 3773/4885
US-12569564-B2 Spirocyclic MDM2 modulator and uses thereof MDM2, TP53, XIAP MAPT 2740/4885ALDH1A1 1320/4885KDM4E 3943/4885
US-12612412-B2 Antiviral heterocyclic compounds ZC3HAV1, NHERF1, HM13 MAPT 4663/4885ALDH1A1 4093/4885KDM4E 342/4885
US-20260014261-A1 TARGETED PROTEIN MODIFICATION MDM2, TP53, VHL MAPT 963/4885ALDH1A1 4015/4885KDM4E 1602/4885
US-20260098032-A1 METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION TP53, TP53BP1, MDM2 MAPT 2371/4885ALDH1A1 4027/4885KDM4E 1371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.