Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12238070 | 1.00 | LMNA (0.36) | LMNAGAASMN1; SMN2KMT2ARECQL | |
| SCHEMBL18118469 | 0.94 | ALOX15 (0.37) | LMNAGAASMN1; SMN2KMT2ARECQL | |
| SCHEMBL12906770 | 0.94 | ALOX15 (0.37) | LMNAGAASMN1; SMN2KMT2ARECQL | |
| SCHEMBL10475746 | 0.94 | ALOX15 (0.37) | LMNAGAASMN1; SMN2KMT2ARECQL | |
| SCHEMBL560792 | 0.92 | HSD17B10 (0.39) | SMN1; SMN2KMT2AHSD17B10MEN1ALDH1A1 | |
| SCHEMBL15518427 | 0.92 | HSD17B10 (0.39) | SMN1; SMN2KMT2AHSD17B10MEN1ALDH1A1 | |
| SCHEMBL17053358 | 0.88 | HSD17B10 (0.36) | SMN1; SMN2KMT2AHSD17B10MEN1ALDH1A1 | |
| SCHEMBL17057486 | 0.88 | HSD17B10 (0.36) | SMN1; SMN2KMT2AHSD17B10MEN1ALDH1A1 | |
| SCHEMBL30069168 | 0.85 | PLA2G10 (0.35) | KMT2AHSD17B10MEN1ALDH1A1 | |
| SCHEMBL14522328 | 0.84 | CHRM5 (0.35) | HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065384-A1 | FLUORESCENT MRI PROBE | THE UNIVERSITY OF TOKYO (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065384-A1 | FLUORESCENT MRI PROBE | GLRA1, GLRA3, GDI1 | LMNA 2272/4885GAA 1756/4885SMN1; SMN2 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.