Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539638 | 0.89 | CA2 (0.33) | RARGRXRAPPARGGABRA1POLB | |
| SCHEMBL1795642 | 0.79 | CA1 (0.50) | GABRA1GABRB2GAAMAPT | |
| SCHEMBL4775793 | 0.79 | CA1 (0.50) | GABRA1GABRB2GAAMAPT | |
| SCHEMBL16785956 | 0.79 | GABRA1 (0.38) | RARGRXRAPPARGGABRA1GABRB2 | |
| SCHEMBL15540035 | 0.78 | ADRA2A (0.43) | PPARGPOLBGAAGFER | |
| SCHEMBL15794454 | 0.78 | TUBB1 (0.36) | GABBR2GABBR1MAPK14 | |
| SCHEMBL14320994 | 0.76 | ALDH1A1 (0.39) | GAAMAPT | |
| SCHEMBL14640958 | 0.76 | GABRA1 (0.46) | RARGRXRAPPARGGABRA1GABRB2 | |
| SCHEMBL15539512 | 0.75 | GLRA1 (0.56) | MAPT | |
| SCHEMBL23436794 | 0.73 | AKR1C3 (0.37) | POLBGAAGFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422248-B2 | Phenyl- and pyridinyl-substituted 2,2,2-trifluoroethanols having anticonvulsant properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-08-23 | — | — | US | claimed |
| US-20150158821-A1 | SUBSTITUTED PHENOLS HAVING ANTICONVULSANT PROPERTIES | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2015-06-11 | — | — | US | claimed |
| WO-2013188716-A1 | SUBSTITUTED PHENOLS HAVING ANTICONVULSANT PROPERTIES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-12-19 | — | — | WO | claimed |
| US-9422248-B2 | Phenyl- and pyridinyl-substituted 2,2,2-trifluoroethanols having anticonvulsant properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422248-B2 | Phenyl- and pyridinyl-substituted 2,2,2-trifluoroethanols having anticonvulsant properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150158821-A1 | SUBSTITUTED PHENOLS HAVING ANTICONVULSANT PROPERTIES | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2015-06-11 | — | — | US | disclosed |
| US-20150158821-A1 | SUBSTITUTED PHENOLS HAVING ANTICONVULSANT PROPERTIES | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2015-06-11 | — | — | US | disclosed |
| WO-2013188716-A1 | SUBSTITUTED PHENOLS HAVING ANTICONVULSANT PROPERTIES | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158821-A1 | SUBSTITUTED PHENOLS HAVING ANTICONVULSANT PROPERTIES | PNMT, COMT, GABRE | RARG 946/4885RXRA 322/4885PPARG 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.