Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775793 | 1.00 | CA1 (0.50) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL15539232 | 0.88 | GABRA1 (0.44) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL15539085 | 0.79 | RECQL (0.41) | GABRA1GABRB2LMNATSHRPTGS1 | |
| SCHEMBL15538701 | 0.79 | RARG (0.34) | GABRA1GABRB2GAAMAPT | |
| SCHEMBL94533 | 0.75 | GABRA1 (0.77) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL3281421 | 0.74 | GABRA1 (0.65) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL7117823 | 0.74 | GABRA1 (0.35) | CA1CA2GABRA1GABRB2LMNA | |
| Ammonia Solution, Strong SCHEMBL28098766 | 0.73 | GABRA1 (0.74) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL10966386 | 0.73 | CA1 (0.64) | CA1CA2GABRA1GABRB2GABRB1 | |
| SCHEMBL15539638 | 0.73 | CA2 (0.33) | CA2GABRA1GABRB1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951979-B2 | 2,4,6-trisubstituted phenols having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2011-05-31 | — | — | US | claimed |
| US-20100173997-A1 | 2,4,6-TRISUBSTITUTED PHENOLS HAVING ANESTHETIC PROPERTIES | University of Iowa Research Foundatiion (US) | 2010-07-08 | — | — | US | claimed |
| US-7678946-B2 | 2,4,6,-trisubstituted having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2010-03-16 | — | — | US | claimed |
| US-20080114073-A1 | 2,4,6,-Trisubstituted phenols having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2008-05-15 | — | — | US | claimed |
| WO-2008008498-A2 | 2, 4, 6-TRISUBSTITUTED PHENOLS HAVING ANESTHETIC PROPERTIES | UNIVERSITY OF IOWA RESEARCH FDTN. (US) | 2008-01-17 | — | — | WO | claimed |
| WO-2026102432-A1 | HUMAN ANTIBODIES TO MARBURG VIRUS AND METHODS OF USE THEREFOR | VANDERBILT UNIVERSITY (US) | 2026-05-15 | — | — | WO | disclosed |
| WO-2025262636-A1 | RNA BIOSENSOR AND GENE THERAPY CONTROLLER USING DISEASE-SPECIFIC CRYPTIC EXON RETENTION | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2025-12-26 | — | — | WO | disclosed |
| US-20250333517-A1 | ENGINEERED GLYCOPROTEIN POPULATION AND USES THEREOF | ROCK BIOMEDICAL INC (TW) | 2025-10-30 | — | — | US | disclosed |
| WO-2025226309-A1 | ENGINEERED GLYCOPROTEIN POPULATION AND USES THEREOF | ROCK BIOMEDICAL INC. (TW) | 2025-10-30 | — | — | WO | disclosed |
| US-20250333518-A1 | ENGINEERED GLYCOPROTEIN POPULATION AND USES THEREOF | ROCK BIOMEDICAL INC (TW) | 2025-10-30 | — | — | US | disclosed |
| WO-2025226354-A1 | ENGINEERED GLYCOPROTEIN POPULATION AND USES THEREOF | ROCK BIOMEDICAL, INC. (TW) | 2025-10-30 | — | — | WO | disclosed |
| CN-120192406-A | Nanometer antibody for inhibiting infection of present Dibujiao type and zadil type Ebola viruses | 中国医学科学院病原生物学研究所 | 2025-06-24 | — | — | CN | disclosed |
| US-7678946-B2 | 2,4,6,-trisubstituted having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2010-03-16 | — | — | US | disclosed |
| US-20080119566-A1 | Hydrofluoroalkyl phenols having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2008-05-22 | — | — | US | disclosed |
| US-20080114073-A1 | 2,4,6,-Trisubstituted phenols having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2008-05-15 | — | — | US | disclosed |
| US-20080114073-A1 | 2,4,6,-Trisubstituted phenols having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2008-05-15 | — | — | US | disclosed |
| US-20080114073-A1 | 2,4,6,-Trisubstituted phenols having anesthetic properties | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2008-05-15 | — | — | US | disclosed |
| WO-2008008492-A2 | HYDROFLUOROALKYL PHENOLS HAVING ANESTHETIC PROPERTIES | UNIVERSITY OF IOWA RESEARCH FDTN. (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008008498-A2 | 2, 4, 6-TRISUBSTITUTED PHENOLS HAVING ANESTHETIC PROPERTIES | UNIVERSITY OF IOWA RESEARCH FDTN. (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2008008498-A2 | 2, 4, 6-TRISUBSTITUTED PHENOLS HAVING ANESTHETIC PROPERTIES | UNIVERSITY OF IOWA RESEARCH FDTN. (US) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173997-A1 | 2,4,6-TRISUBSTITUTED PHENOLS HAVING ANESTHETIC PROPERTIES | OPRK1, OPRM1, OPRL1 | CA1 594/4885CA2 559/4885GABRA1 201/4885 |
| US-20080114073-A1 | 2,4,6,-Trisubstituted phenols having anesthetic properties | OPRK1, OPRM1, OPRD1 | CA1 472/4885CA2 524/4885GABRA1 260/4885 |
| US-20080119566-A1 | Hydrofluoroalkyl phenols having anesthetic properties | OPRL1, VHL, PPARG | CA1 397/4885CA2 535/4885GABRA1 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.