Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | DDX3X | O00571 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138425 | 0.87 | TSHR (0.55) | TSHRKCNMA1TDP1L3MBTL1MEN1 | |
| SCHEMBL5110430 | 0.87 | TSHR (0.59) | TSHRKCNMA1TDP1L3MBTL1MEN1 | |
| SCHEMBL305239 | 0.83 | TSHR (0.63) | TSHRKCNMA1TDP1L3MBTL1MEN1 | |
| SCHEMBL28102854 | 0.83 | TSHR (0.51) | TSHRKCNMA1TDP1L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL7418132 | 0.82 | TSHR (0.61) | TSHRKCNMA1TDP1L3MBTL1MEN1 | |
| SCHEMBL7253753 | 0.81 | KCNMA1 (0.57) | TSHRKCNMA1TDP1L3MBTL1MEN1 | |
| SCHEMBL7253758 | 0.81 | KCNMA1 (0.57) | TSHRKCNMA1TDP1L3MBTL1MEN1 | |
| SCHEMBL4609558 | 0.81 | ALDH1A1 (0.54) | TSHRKCNMA1L3MBTL1MEN1KMT2A | |
| SCHEMBL11522358 | 0.81 | TSHR (0.49) | TSHRKCNMA1TDP1L3MBTL1MEN1 | |
| SCHEMBL11522354 | 0.81 | TSHR (0.49) | TSHRKCNMA1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486040-B1 | AUTOMATED RADIOSYNTHESIS | GE HEALTHCARE LTD (GB) | 2017-06-21 | — | — | EP | disclosed |
| US-8946410-B2 | Automated radiosynthesis | GE HEALTHCARE LIMITED (GB) | 2015-02-03 | — | — | US | disclosed |
| EP-2486040-A1 | AUTOMATED RADIOSYNTHESIS | GE Healthcare Limited (GB) | 2012-08-15 | — | — | EP | disclosed |
| US-20120190843-A1 | AUTOMATED RADIOSYNTHESIS | GE HEALTHCARE LIMITED (GB) | 2012-07-26 | — | — | US | disclosed |
| WO-2011042529-A1 | AUTOMATED RADIOSYNTHESIS | GE HEALTHCARE LIMITED (GB) | 2011-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190843-A1 | AUTOMATED RADIOSYNTHESIS | GABRB2, GABRB3, GABRR2 | TSHR 174/4885KCNMA1 1719/4885TDP1 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.