Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6299216 | 0.81 | PYCR1 (0.47) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL29680819 | 0.81 | SLC6A4 (0.39) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL844672 | 0.81 | SLC6A4 (0.39) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL1561687 | 0.80 | CYP2A6 (0.35) | ALDH1A1PYCR1CCR5SMN1; SMN2CYP1A2 | |
| SCHEMBL154181 | 0.79 | PTGDR2 (0.44) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL16036319 | 0.79 | SLC6A4 (0.38) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL30609710 | 0.79 | SLC6A4 (0.38) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL43286 | 0.79 | GABRA1 (0.44) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL1758977 | 0.79 | CCR5 (0.49) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL29426994 | 0.79 | GABRA1 (0.44) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332733-B | Dapagliflozin middle Synthesis process of intermediate | 江苏阿尔法药业股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| US-20240343740-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY | 2024-10-17 | — | — | US | disclosed |
| CN-117658784-B | Dapagliflozin middle Process for the preparation of intermediates | 山东诚汇双达药业有限公司 | 2024-09-13 | — | — | CN | disclosed |
| EP-4341255-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-117658784-A | Preparation method of dapagliflozin intermediate | 山东诚汇双达药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117355517-A | Macrocyclic glucagon-like peptide 1 receptor agonists | 伊莱利利公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-116332733-A | Synthesis process of dapagliflozin intermediate | 江苏阿尔法药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022246019-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2022-11-24 | — | — | WO | disclosed |
| CN-114773373-A | Preparation method of engagliflozin key intermediate and engagliflozin impurity | 浙江普洛家园药业有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-109111463-B | Method for producing aromatic compound | DIC株式会社 | 2022-07-01 | — | — | CN | disclosed |
| US-20070073046-A1 | Processes for preparing of glucopyranosyl-substituted (ethynyl-benzyl)-benzene derivatives and intermediates thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-03-29 | — | — | US | disclosed |
| US-20070073046-A1 | Processes for preparing of glucopyranosyl-substituted (ethynyl-benzyl)-benzene derivatives and intermediates thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-03-29 | — | — | US | disclosed |
| WO-2007031548-A2 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED (ETHYNYL-BENZYL)-BENZENE DERIVATIVES AND INTERMEDIATES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-03-22 | — | — | WO | disclosed |
| WO-2007031548-A2 | PROCESSES FOR PREPARING OF GLUCOPYRANOSYL-SUBSTITUTED (ETHYNYL-BENZYL)-BENZENE DERIVATIVES AND INTERMEDIATES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-03-22 | — | — | WO | disclosed |
| CN-1829729-A | Novel compounds | TANABE SEIYAKU CO (JP) | 2006-09-06 | — | — | CN | disclosed |
| EP-1651658-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | TANABE SEIYAKU CO., LTD. (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-20050233988-A1 | Novel compounds | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-20 | — | — | US | disclosed |
| WO-2005012326-A1 | NOVEL COMPOUNDS HAVING INHIBITORY ACTIVITY AGAINST SODIUM-DEPENDANT TRANSPORTER | TANABE SEIYAKU CO., LTD. (JP) | 2005-02-10 | — | — | WO | disclosed |
| US-4400388-A | Fungicidal 1-phenyl-2-(1,2,4-triazol-1-yl)-ethyl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-23 | — | — | US | disclosed |
| US-4327104-A | FUNGICIDES AND BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050233988-A1 | Novel compounds | CYP1B1, CYP4B1, CYP2B6 | SLC6A4 1583/4885HTR2A 2962/4885KCNH2 1113/4885 |
| US-20240343740-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | GLP1R, GCGR, GIPR | SLC6A4 3233/4885HTR2A 857/4885KCNH2 790/4885 |
| US-20070073046-A1 | Processes for preparing of glucopyranosyl-substituted (ethynyl-benzyl)-benzene derivatives and intermediates thereof | UGGT1, B3GAT3, UGCG | SLC6A4 3774/4885HTR2A 3643/4885KCNH2 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.