Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844672 | 1.00 | SLC6A4 (0.39) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| Alcohol SCHEMBL1097067 | 0.90 | ALDH1A1 (0.40) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL155606 | 0.81 | SLC6A4 (0.39) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL30345107 | 0.81 | PYCR1 (0.47) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL307792 | 0.81 | PYCR1 (0.47) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL500031 | 0.80 | SLC6A4 (0.37) | SLC6A4HTR2AKCNH2ALDH1A1CCR5 | |
| SCHEMBL43286 | 0.79 | GABRA1 (0.44) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL1758977 | 0.79 | CCR5 (0.49) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL154181 | 0.79 | PTGDR2 (0.44) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 | |
| SCHEMBL16036319 | 0.79 | SLC6A4 (0.38) | SLC6A4HTR2AKCNH2ALDH1A1PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332882-B | Synthesis process of key intermediate of englitz | 江苏阿尔法集团福瑞药业(宿迁)有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-116332882-B | Synthesis process of key intermediate of englitz | 江苏阿尔法集团福瑞药业(宿迁)有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-116332733-B | Dapagliflozin middle Synthesis process of intermediate | 江苏阿尔法药业股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| EP-4341255-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | Eli Lilly and Company (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-117402081-A | Aryl substituted amine derivative, preparation method and application thereof | 南京医科大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-117355517-A | Macrocyclic glucagon-like peptide 1 receptor agonists | 伊莱利利公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-4262807-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-116332882-A | Synthesis process of key intermediate of englitz | 江苏福瑞康泰药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116332882-A | Synthesis process of key intermediate of englitz | 江苏福瑞康泰药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116332733-A | Synthesis process of dapagliflozin intermediate | 江苏阿尔法药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2022246019-A1 | MACROCYCLIC GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2022-11-24 | — | — | WO | disclosed |
| WO-2022132200-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |