Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17494763 | 0.84 | ALDH1A1 (0.49) | PTGDR2ALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL3455233 | 0.83 | SMN1; SMN2 (0.40) | PTGDR2ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL30467771 | 0.82 | PYCR1 (0.46) | PTGDR2ALDH1A1SMN1; SMN2LMNASLC6A4 | |
| SCHEMBL307760 | 0.82 | PYCR1 (0.46) | PTGDR2ALDH1A1SMN1; SMN2LMNASLC6A4 | |
| SCHEMBL499287 | 0.81 | SLC5A2 (0.38) | PTGDR2SMN1; SMN2LMNANPSR1SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL23833320 | 0.80 | PYCR1 (0.45) | PTGDR2ALDH1A1SMN1; SMN2LMNASLC6A4 | |
| Alcohol SCHEMBL1097067 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2LMNANPSR1SLC6A4 | |
| SCHEMBL9503395 | 0.79 | ALDH1A1 (0.42) | PTGDR2ALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL155606 | 0.79 | SLC6A4 (0.39) | ALDH1A1SMN1; SMN2LMNANPSR1SLC6A4 | |
| SCHEMBL844672 | 0.79 | SLC6A4 (0.39) | ALDH1A1SMN1; SMN2LMNANPSR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744227-A | 5-bromine-2-chlorobenzaldehyde preparation method | PORTON FINE CHEMICALS LTD | 2015-07-01 | — | — | CN | claimed |
| US-12559504-B2 | Benzotriazole derivative | UBE CORPORATION (JP) | 2026-02-24 | — | — | US | disclosed |
| US-12509467-B2 | CGAS inhibiting triazolopyrimidone derivatives | HOFFMANN-LA ROCHE INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-20250388615-A9 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2025-12-25 | — | — | US | disclosed |
| EP-3978073-B1 | 1H-BENZO[D][1,2,3]TRIAZOLE DERIVATIVES AS KEAP1 INHIBITORS FOR THE TREATMENT OF RENAL DISEASES | UBE CORP (JP) | 2025-10-15 | — | — | EP | disclosed |
| CN-114174289-B | Benzotriazole derivatives | ＵＢＥ株式会社 | 2025-03-07 | — | — | CN | disclosed |
| US-20250066410-A1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2025-02-27 | — | — | US | disclosed |
| CN-119504706-A | Macrocyclic compounds having farnesyl transferase inhibitory activity | 库拉肿瘤学公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-4441038-A1 | MACROCYCLIC COMPOUNDS HAVING FARNESYLTRANSFERASE INHIBITORY ACTIVITY | Kura Oncology, Inc. (US) | 2024-10-09 | — | — | EP | disclosed |
| US-12084472-B2 | Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists | ARDELYX, INC. (US) | 2024-09-10 | — | — | US | disclosed |
| US-6489487-B1 | AGRICULTURAL OR HORTICULTURAL FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-03 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |
| US-6313071-B1 | Phenylacetylene derivatives and agricultural/horticultural fungicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1103548-A1 | TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-05-30 | — | — | EP | disclosed |
| EP-1085010-A1 | PHENYLACETYLENE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-0328643-B1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO CORP (JP) | 1994-07-06 | — | — | EP | disclosed |
| WO-1993008166-A1 | BENZO-ISOQUINOLINE DERIVATIVES AND ANALOGS AND THEIR USE IN THERAPEUTICS | THE UPJOHN COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0539209-A1 | Benzo-isoquinoline derivatives and analogs and their use in therapeutics | THE UPJOHN COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5043142-A | Measuring peroxide-active substances | TERUMO KABUSHIKI KAISHA (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0328643-A1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO KABUSHIKI KAISHA (JP) | 1989-08-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12509467-B2 | CGAS inhibiting triazolopyrimidone derivatives | CGAS, STING1, IRF3 | PTGDR2 2461/4885ALDH1A1 1347/4885SMN1; SMN2 3508/4885 |
| US-12559504-B2 | Benzotriazole derivative | KEAP1, NFE2L2, NCOR1 | PTGDR2 2194/4885ALDH1A1 198/4885SMN1; SMN2 2707/4885 |
| US-20250066410-A1 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | GPR119, GIPR, GLP1R | PTGDR2 160/4885ALDH1A1 4357/4885SMN1; SMN2 2199/4885 |
| US-20250388615-A9 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | GPR119, GIPR, FFAR3 | PTGDR2 733/4885ALDH1A1 3776/4885SMN1; SMN2 1491/4885 |
| US-12084472-B2 | Substituted 4-phenyl pyridine compounds as non-systemic TGR5 agonists | GPR119, GIPR, GLP1R | PTGDR2 160/4885ALDH1A1 4357/4885SMN1; SMN2 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.