Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MB | P02144 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5774866 | 0.90 | KMT2A (0.39) | KMT2AL3MBTL1POLBGAAPKM | |
| SCHEMBL11015282 | 0.86 | KMT2A (0.37) | KMT2AL3MBTL1POLBGAAPKM | |
| SCHEMBL7756861 | 0.80 | KMT2A (0.41) | KMT2APOLBGAAALDH1A1MAPT | |
| SCHEMBL15565552 | 0.80 | KMT2A (0.41) | KMT2AL3MBTL1POLBALDH1A1MAPT | |
| SCHEMBL15564197 | 0.73 | L3MBTL1 (0.54) | KMT2AL3MBTL1POLBGAAPKM | |
| SCHEMBL12766932 | 0.71 | POLB (0.54) | L3MBTL1POLBALDH1A1MAPTCYP1A2 | |
| SCHEMBL3804852 | 0.71 | KMT2A (0.38) | KMT2APOLBGAAALDH1A1MAPT | |
| SCHEMBL11131428 | 0.71 | ALDH1A1 (0.37) | L3MBTL1GAAPKMALDH1A1MAPT | |
| SCHEMBL15565380 | 0.70 | ALPL (0.55) | KMT2APOLBALDH1A1MAPTLMNA | |
| SCHEMBL19512658 | 0.70 | CYP1A2 (0.44) | L3MBTL1POLBGAAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882720-A1 | A PROCESS FOR THE PREPARATION OF AN INTERMEDIATE FOR A TRIAZOLOPYRIMIDINE CARBONUCLEOSIDE | Enantia, S.L. (ES) | 2015-06-17 | — | — | EP | disclosed |
| US-20150152114-A1 | PROCESS FOR THE PREPARATION OF AN INTERMEDIATE FOR A TRIAZOLOPYRIMIDINE CARBONUCLEOSIDE | ENANTIA, S.L. (ES) | 2015-06-04 | — | — | US | disclosed |
| US-20150152114-A1 | PROCESS FOR THE PREPARATION OF AN INTERMEDIATE FOR A TRIAZOLOPYRIMIDINE CARBONUCLEOSIDE | ENANTIA, S.L. (ES) | 2015-06-04 | — | — | US | disclosed |
| US-20150152114-A1 | PROCESS FOR THE PREPARATION OF AN INTERMEDIATE FOR A TRIAZOLOPYRIMIDINE CARBONUCLEOSIDE | ENANTIA, S.L. (ES) | 2015-06-04 | — | — | US | disclosed |
| WO-2014023681-A1 | A PROCESS FOR THE PREPARATION OF AN INTERMEDIATE FOR A TRIAZOLOPYRIMIDINE CARBONUCLEOSIDE | ENANTIA, S.L. (ES) | 2014-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152114-A1 | PROCESS FOR THE PREPARATION OF AN INTERMEDIATE FOR A TRIAZOLOPYRIMIDINE CARBONUCLEOSIDE | NUDT1, DUT, UMPS | KMT2A 2681/4885L3MBTL1 4741/4885POLB 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.