Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501627 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HSPB1MEN1KMT2AMAPT | |
| SCHEMBL6809251 | 0.81 | PDK1 (0.58) | CYP19A1ALDH1A1HSPB1MEN1KMT2A | |
| SCHEMBL29749825 | 0.81 | PDK1 (0.58) | CYP19A1ALDH1A1HSPB1MEN1KMT2A | |
| SCHEMBL6575768 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HSPB1MEN1KMT2AMAPT | |
| SCHEMBL9638881 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HSPB1MEN1KMT2AMAPT | |
| SCHEMBL11583868 | 0.75 | XDH (0.49) | CYP19A1ALDH1A1HSPB1MEN1KMT2A | |
| SCHEMBL3586660 | 0.74 | TTR (0.55) | ALDH1A1HSPB1MEN1KMT2AMAPT | |
| SCHEMBL7824974 | 0.74 | TTR (0.55) | ALDH1A1HSPB1MEN1KMT2AMAPT | |
| SCHEMBL30951750 | 0.72 | ALDH1A1 (0.51) | CYP19A1ALDH1A1HSPB1MEN1KMT2A | |
| SCHEMBL9655460 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HSPB1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885270-A1 | DYE COMPOSITION COMPRISING A CATIONIC O-ALKYL-SUBSTITUTED META-PHENYLENEDIAMINE DERIVATIVE | L'Oréal (FR) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014026952-A1 | DYE COMPOSITION COMPRISING A CATIONIC O-ALKYL-SUBSTITUTED META-PHENYLENEDIAMINE DERIVATIVE | L'OREAL (FR) | 2014-02-20 | — | — | WO | disclosed |