SCHEMBL15569024

SCHEMBL15569024

O=[N+]([O-])c1ccc(Br)cc1-c1cccc2ccn(-c3ccccc3)c12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 1/20 0.39
▸ GABRA1 P14867 2/20 0.37
▸ GABRG2 P18507 2/20 0.37
▸ GABRB3 P28472 2/20 0.37
▸ GABRA5 P31644 2/20 0.37
▸ GABRA3 P34903 2/20 0.37
▸ GABRA2 P47869 2/20 0.37
▸ GABRP O00591 1/20 0.37
▸ GABRD O14764 1/20 0.37
▸ GABRB1 P18505 1/20 0.37
▸ GABRB2 P47870 1/20 0.37
▸ GABRA4 P48169 1/20 0.37
▸ GABRE P78334 1/20 0.37
▸ GABRA6 Q16445 1/20 0.37
▸ GABRG1 Q8N1C3 1/20 0.37
▸ GABRG3 Q99928 1/20 0.37
▸ GABRQ Q9UN88 1/20 0.37
▸ ALDH1A1 P00352 2/20 0.36
▸ TDP1 Q9NUW8 1/20 0.36
▸ ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15801784 0.89 PTGES (0.37) FGFR1GABRA1GABRG2GABRB3GABRA5
SCHEMBL15596393 0.86 FGFR1 (0.48) FGFR1ALDH1A1TDP1S100A4TUBB4A
SCHEMBL15594724 0.81 GABRA1 (0.40) FGFR1GABRA1GABRG2GABRB3GABRA5
SCHEMBL15481629 0.78 PLA2G4A (0.39) FGFR1GABRA1GABRG2GABRB3GABRA5
SCHEMBL15562879 0.78 ALDH1A1 (0.36) FGFR1GABRA1GABRG2GABRB3GABRA5
SCHEMBL15801729 0.77 FGFR1 (0.44) FGFR1ALDH1A1TDP1S100A4TUBB4A
SCHEMBL13828961 0.75 ALDH1A1 (0.53) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15796880 0.74 FGFR1 (0.44) FGFR1ALDH1A1TDP1S100A4LMNA
SCHEMBL17029042 0.74 ALDH1A1 (0.39) FGFR1ALDH1A1TDP1S100A4LMNA
SCHEMBL15596418 0.74 HDAC3 (0.38) GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11456422-B2 Compound and organic electroluminescent device comprising same SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2022-09-27 — — US disclosed
US-20190157567-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME DOOSAN CORPORATION (KR) 2019-05-23 — — US disclosed
US-20190157567-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME DOOSAN CORPORATION (KR) 2019-05-23 — — US disclosed
US-10297759-B2 Compound and organic electroluminescent device comprising same DOOSAN CORPORATION (KR) 2019-05-21 — — US disclosed
US-10297759-B2 Compound and organic electroluminescent device comprising same DOOSAN CORPORATION (KR) 2019-05-21 — — US disclosed
US-9905777-B2 Compound and organic electroluminescence device comprising same DOOSAN CORPORATION (KR) 2018-02-27 — — US disclosed
US-9905777-B2 Compound and organic electroluminescence device comprising same DOOSAN CORPORATION (KR) 2018-02-27 — — US disclosed
US-9905777-B2 Compound and organic electroluminescence device comprising same DOOSAN CORPORATION (KR) 2018-02-27 — — US disclosed
US-20150318483-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME DOOSAN CORPORATION (KR) 2015-11-05 — — US disclosed
US-20150318483-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME DOOSAN CORPORATION (KR) 2015-11-05 — — US disclosed
US-20150236271-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME DOOSAN CORPORATION (KR) 2015-08-20 — — US disclosed
US-20150236271-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME DOOSAN CORPORATION (KR) 2015-08-20 — — US disclosed
US-20150236271-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME DOOSAN CORPORATION (KR) 2015-08-20 — — US disclosed
WO-2014081133-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-05-30 — — WO disclosed
WO-2014081147-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-05-30 — — WO disclosed
WO-2014081133-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-05-30 — — WO disclosed
WO-2014081147-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-05-30 — — WO disclosed
WO-2014027814-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-02-20 — — WO disclosed
WO-2014027814-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-02-20 — — WO disclosed
WO-2014025209-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME 주식회사 두산 (KR) 2014-02-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10297759-B2 Compound and organic electroluminescent device comprising same TMEM109, L1CAM, OR10J3 FGFR1 4662/4885GABRA1 3369/4885GABRG2 3495/4885
US-20150318483-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SLC18A3, L1CAM, TMEM109 FGFR1 4700/4885GABRA1 3899/4885GABRG2 4041/4885
US-20190157567-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SLC18A3, L1CAM, TMEM109 FGFR1 4700/4885GABRA1 3899/4885GABRG2 4041/4885
US-11456422-B2 Compound and organic electroluminescent device comprising same TMEM109, L1CAM, OR10J3 FGFR1 4662/4885GABRA1 3369/4885GABRG2 3495/4885
US-20150236271-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME OR10J3, VDAC1, VDAC2 FGFR1 4646/4885GABRA1 4306/4885GABRG2 4455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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