Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368529 | 0.85 | PGR (0.46) | CYP2C9PGR | |
| SCHEMBL2188047 | 0.79 | HDAC8 (0.31) | HDAC8CYP2C9 | |
| SCHEMBL419847 | 0.76 | LMNA (0.57) | PGR | |
| SCHEMBL3619202 | 0.75 | PGR (0.58) | PGRCA12CA2CA9CA14 | |
| SCHEMBL2763490 | 0.75 | PGR (0.33) | PGR | |
| SCHEMBL28871 | 0.74 | HDAC8 (0.59) | HDAC8CYP2C9CA12CA1CA2 | |
| SCHEMBL9400014 | 0.72 | GABRP (0.35) | HDAC8CYP2C9GABRPGABRDGABRA1 | |
| SCHEMBL7195361 | 0.71 | CA12 (0.39) | HDAC8CYP2C9CA12CA1CA2 | |
| SCHEMBL5185591 | 0.71 | APP (0.55) | CYP2C9CA12CA1CA2CA9 | |
| SCHEMBL10481152 | 0.71 | HDAC8 (0.56) | HDAC8CYP2C9CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114618450-B | Conjugated microporous polymer composite material, preparation method thereof and adsorbent | 北京石墨烯技术研究院有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-114618450-A | Conjugated microporous polymer composite material, preparation method thereof and adsorbent | 北京石墨烯技术研究院有限公司 | 2022-06-14 | — | — | CN | claimed |
| CN-118613316-A | System and method for direct air capture of water and CO2 | 巴特尔纪念研究院 | 2024-09-06 | — | — | CN | disclosed |
| US-20230294033-A1 | ULTRAMICRO TO MESOPORE FRAMEWORKS FOR SELECTIVE SEPARATION AND STORAGE OF NOBLE GASES | BATTELLE MEMORIAL INSTITUTE (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230264138-A1 | SYSTEM AND METHOD FOR DIRECT AIR CAPTURE OF WATER AND CO2 | BATTELLE MEMORIAL INSTITUTE | 2023-08-24 | — | — | US | disclosed |
| WO-2023146800-A1 | SYSTEM AND METHOD FOR DIRECT AIR CAPTURE OF WATER AND CO2 | BATTELLE MEMORIAL INSTITUTE (US) | 2023-08-03 | — | — | WO | disclosed |
| US-20230233989-A1 | SYSTEM AND METHOD FOR DIRECT AIR CAPTURE OF WATER AND CO2 | BATTELLE MEMORIAL INSTITUTE (US) | 2023-07-27 | — | — | US | disclosed |
| CN-114920907-B | Aminated porous aromatic skeleton compound and preparation method and application thereof | 福建农林大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-114920907-A | Aminated porous aromatic skeleton compound and preparation method and application thereof | 福建农林大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114618450-B | Conjugated microporous polymer composite material, preparation method thereof and adsorbent | 北京石墨烯技术研究院有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-114618450-A | Conjugated microporous polymer composite material, preparation method thereof and adsorbent | 北京石墨烯技术研究院有限公司 | 2022-06-14 | — | — | CN | disclosed |
| US-11318409-B2 | Ultramicro to mesopore frameworks for selective separation and storage of noble gases | BATTELLE MEMORIAL INSTITUTE (US) | 2022-05-03 | — | — | US | disclosed |
| US-10266737-B2 | Adsorption systems using metal-organic frameworks | ARKEMA INC. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20190091623-A1 | ULTRAMICRO TO MESOPORE FRAMEWORKS FOR SELECTIVE SEPARATION AND STORAGE OF NOBLE GASES | BATTELLE MEMORIAL INSTITUTE (US) | 2019-03-28 | — | — | US | disclosed |
| CN-105026854-A | Adsorption systems using metal-organic frameworks | ARKEMA INC | 2015-11-04 | — | — | CN | disclosed |
| US-20150291870-A1 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. | 2015-10-15 | — | — | US | disclosed |
| EP-2885365-A2 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | Arkema, Inc. (US) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014028574-A9 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| WO-2014028574-A2 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | ARKEMA INC. (US) | 2014-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291870-A1 | ADSORPTION SYSTEMS USING METAL-ORGANIC FRAMEWORKS | PFAS, CHIA, PARN | HDAC8 382/4885CYP2C9 1686/4885PGR 883/4885 |
| US-10266737-B2 | Adsorption systems using metal-organic frameworks | PFAS, CHIA, PARN | HDAC8 382/4885CYP2C9 1686/4885PGR 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.