Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370923 | 0.78 | ITGB3 (0.43) | ALDH1A1RAB9ANPC1HPGDAGTR1 | |
| SCHEMBL18033882 | 0.78 | ALDH1A1 (0.42) | ALDH1A1RAB9ANPC1HPGDAGTR1 | |
| SCHEMBL2525700 | 0.76 | PRSS1 (0.62) | ITGB3ITGA2BPRSS1F2 | |
| SCHEMBL5692310 | 0.73 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1HPGDAGTR1 | |
| SCHEMBL11718244 | 0.73 | RAB9A (0.71) | ALDH1A1RAB9ANPC1HPGDAGTR1 | |
| SCHEMBL8639589 | 0.72 | L3MBTL1 (0.46) | ALDH1A1RAB9ANPC1HPGDAGTR1 | |
| SCHEMBL8637256 | 0.72 | MAPT (0.52) | ALDH1A1RAB9ANPC1HPGDAGTR1 | |
| Phosphonic Acid SCHEMBL15485473 | 0.72 | PRSS1 (0.57) | ITGB3ITGA2BPRSS1F2 | |
| SCHEMBL29051542 | 0.71 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1HPGDAGTR1 | |
| SCHEMBL28670574 | 0.71 | LMNA (0.50) | ALDH1A1RAB9ANPC1HPGDAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014041559-A2 | PROCESS FOR THE PREPARATION OF DABIGATRAN ETEXILATE AND INTERMEDIATES THEREOF | GLENMARK PHARMACEUTICALS LIMITED; GLENMARK GENERICS LIMITED (IN) | 2014-03-20 | — | — | WO | disclosed |