Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.65 |
| ▸ | TOP1 | P11387 | 4/20 | 0.44 |
| ▸ | CYCS | P99999 | 3/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tmpyp4 SCHEMBL265519 | 0.82 | TERT (0.97) | TERTTOP1CYCSABCG2ENPP2 | |
| Tmpyp4 SCHEMBL29369473 | 0.80 | TERT (1.00) | TERTTOP1CYCSABCG2ENPP2 | |
| Tmpyp4 SCHEMBL20380171 | 0.80 | TERT (0.93) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL15580415 | 0.79 | TERT (0.80) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL22461492 | 0.79 | TERT (0.58) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL22461491 | 0.79 | TERT (0.58) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL22461493 | 0.79 | TERT (0.58) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL18016429 | 0.78 | TERT (0.82) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL12239740 | 0.78 | TERT (0.51) | TERTTOP1CYCSABCG2ALDH1A1 | |
| SCHEMBL18812590 | 0.77 | TOP1 (0.52) | TERTTOP1CYCSABCG2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346875-B1 | METALLOPORPHYRIN DERIVATIVES, NANOPARTICLES COMPRISING THE SAME, AND USE THEREOF FOR PHOTODYNAMIC THERAPY | CENTRE NAT RECH SCIENT (FR) | 2014-03-19 | — | — | EP | disclosed |