Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.52 |
| ▸ | CYCS | P99999 | 3/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38662506 | 0.80 | TOP1 (0.56) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL8994447 | 0.79 | TOP1 (0.60) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL15580416 | 0.77 | TERT (0.65) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL6394334 | 0.76 | TERT (0.57) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL9910535 | 0.75 | ABCG2 (0.55) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL7241022 | 0.74 | TOP1 (0.58) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL14077524 | 0.74 | ABCG2 (0.54) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL3424111 | 0.74 | TOP1 (0.81) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL499290 | 0.74 | TOP1 (0.65) | TOP1CYCSENPP2ABCG2TERT | |
| SCHEMBL5013660 | 0.74 | TOP1 (0.56) | TOP1CYCSENPP2ABCG2TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253591-A1 | DERIVATIVES OF PORPHYRINS, THEIR PROCESS OF PREPARATION AND THEIR USE FOR TREATING VIRAL INFECTIONS | INST NAT SANTE RECH MED (FR) | 2021-08-19 | — | — | US | disclosed |
| WO-2017072319-A1 | DERIVATIVES OF PORPHYRINS, THEIR PROCESS OF PREPARATION AND THEIR USE FOR TREATING VIRAL INFECTIONS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253591-A1 | DERIVATIVES OF PORPHYRINS, THEIR PROCESS OF PREPARATION AND THEIR USE FOR TREATING VIRAL INFECTIONS | MAVS, ZC3HAV1, ZC3HAV1L | TOP1 159/4885CYCS 964/4885ENPP2 3161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.