Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | S100A4 | P26447 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29430758 | 1.00 | PARP1 (0.53) | PARP1S100A4TRPV1ERN1ABCB1 | |
| SCHEMBL29760341 | 0.83 | S100A4 (0.45) | PARP1S100A4TRPV1ERN1ALDH1A1 | |
| SCHEMBL15009493 | 0.83 | S100A4 (0.45) | PARP1S100A4TRPV1ERN1ALDH1A1 | |
| SCHEMBL1561802 | 0.80 | TSHR (0.56) | S100A4TRPV1ERN1ALDH1A1PKM | |
| SCHEMBL24508 | 0.78 | S100A4 (0.56) | S100A4TRPV1ERN1ABCB1ABCC1 | |
| SCHEMBL29395434 | 0.78 | S100A4 (0.56) | S100A4TRPV1ERN1ABCB1ABCC1 | |
| SCHEMBL204357 | 0.78 | S100A4 (0.61) | S100A4TRPV1ERN1ALDH1A1PKM | |
| SCHEMBL1665978 | 0.78 | PARP1 (0.56) | PARP1ALDH1A1MAPK1CYP3A4LMNA | |
| SCHEMBL30414747 | 0.77 | TDP1 (0.61) | PARP1S100A4ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL3836830 | 0.77 | TDP1 (0.61) | PARP1S100A4ALDH1A1MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026103793-A1 | TRICYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2026-05-21 | — | — | WO | disclosed |
| US-20260103483-A1 | Organometallic Complex And Light-Emitting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2026-04-16 | — | — | US | disclosed |
| US-12514109-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2025-12-30 | — | — | US | disclosed |
| EP-4652154-A1 | NOVEL ALPK1 INHIBITORS | Pyrotech (Beijing) Biotechnology Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| US-12421219-B2 | Compound for organic electronic element, organic electronic element using same, and electronic device comprising same | DUK SAN NEOLUX CO., LTD. (KR) | 2025-09-23 | — | — | US | disclosed |
| CN-119684322-B | Near-infrared luminescent material based on aryl-indole donor, and preparation method and application thereof | 南京邮电大学 | 2025-05-30 | — | — | CN | disclosed |
| US-20250127038-A1 | LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE SAME, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING ELEMENT | SAMSUNG DISPLAY CO., LTD. (KR) | 2025-04-17 | — | — | US | disclosed |
| CN-119775265-A | Light-emitting element, amine compound for light-emitting element, and display device including light-emitting element | 三星显示有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-119751443-A | Nitrogen-containing condensed ring compound, pharmaceutical composition containing same and application thereof | 杭州禹泓医药科技有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119684322-A | Near-infrared luminescent material based on aryl-indole donor, and preparation method and application thereof | 南京邮电大学 | 2025-03-25 | — | — | CN | disclosed |
| US-20100197679-A1 | COMPOUNDS | GLAXO GROUP LIMITED | 2010-08-05 | — | — | US | disclosed |
| US-20100197679-A1 | COMPOUNDS | GLAXO GROUP LIMITED | 2010-08-05 | — | — | US | disclosed |
| WO-2010081894-A1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LIMITED (GB) | 2010-07-22 | — | — | WO | disclosed |
| US-20090054420-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-02-26 | — | — | US | disclosed |
| US-7456196-B2 | Bicyclic-substituted amines as histamine-3 receptor ligands | ABBOTT LABORATORIES (US) | 2008-11-25 | — | — | US | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |
| US-7153889-B2 | Bicyclic-substituted amines as histamine-3 receptor ligands | ABBOTT LABORATORIES (US) | 2006-12-26 | — | — | US | disclosed |
| US-20060194798-A1 | Bicyclic-substituted amines as histamine-3 receptor ligands | ABBVIE INC. | 2006-08-31 | — | — | US | disclosed |
| US-20040152704-A1 | Bicyclic-substituted amines as histamine-3 receptor ligands | ABBVIE INC. | 2004-08-05 | — | — | US | disclosed |
| US-5254776-A | Synthesis of bromobiphenyls | MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194798-A1 | Bicyclic-substituted amines as histamine-3 receptor ligands | HRH3, HRH4, HRH2 | PARP1 3345/4885S100A4 2415/4885TRPV1 258/4885 |
| US-20100197679-A1 | COMPOUNDS | NRDC, MRPL21, NISCH | PARP1 1313/4885S100A4 1221/4885TRPV1 1044/4885 |
| US-12421219-B2 | Compound for organic electronic element, organic electronic element using same, and electronic device comprising same | OR51E2, ETV6, OR10J3 | PARP1 4453/4885S100A4 1715/4885TRPV1 688/4885 |
| US-20090054420-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | HRH3, HRH4, HRH2 | PARP1 3345/4885S100A4 2415/4885TRPV1 258/4885 |
| US-12514109-B2 | Organic electroluminescent materials and devices | LBR, OPRD1, NAP1L1 | PARP1 237/4885S100A4 3231/4885TRPV1 1432/4885 |
| US-20260103483-A1 | Organometallic Complex And Light-Emitting Device | CRY1, ZC3HAV1L, CRY2 | PARP1 2017/4885S100A4 2927/4885TRPV1 4276/4885 |
| US-20040152704-A1 | Bicyclic-substituted amines as histamine-3 receptor ligands | HRH3, HRH4, HRH1 | PARP1 2601/4885S100A4 2055/4885TRPV1 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.