Sugi Predict

Sugi Predict / Compounds / SCHEMBL15639716

SCHEMBL15639716

SCHEMBL15639716

O=C(O)c1cnn(-c2c(F)cccc2F)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ ACMSD Q8TDX5 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ ELOVL1 Q9BW60 1/20 0.37
▸ ALB P02768 1/20 0.37
▸ PLAU P00749 1/20 0.36
▸ ELANE P08246 1/20 0.36
▸ P4HTM Q9NXG6 2/20 0.35
▸ ASPH Q12797 1/20 0.35
▸ KDM8 Q8N371 1/20 0.35
▸ TTR P02766 1/20 0.35
▸ EGLN1 Q9GZT9 1/20 0.35
▸ PTGER1 P34995 1/20 0.34
▸ CES2 O00748 1/20 0.34
▸ CES1 P23141 1/20 0.34
▸ MAPK14 Q16539 1/20 0.33
▸ HDAC1 Q13547 1/20 0.33
▸ ALKBH1 Q13686 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL693372 0.85 CA5A (0.41) KDM4EELOVL1PLAUELANECES2
SCHEMBL23354698 0.83 ADAMTS7 (0.38) KDM4EALOX15TSHRACMSDTDP1
SCHEMBL23354796 0.82 ADAMTS7 (0.47) KDM4EALOX15ELOVL1P4HTMMAPK14
SCHEMBL22968427 0.81 HCRTR1 (0.40) PLAUELANECES2CES1ADAMTS7
SCHEMBL15638776 0.81 MAPT (0.39) KDM4EKMT2A
SCHEMBL23354743 0.78 NAPRT (0.39) KDM4ETDP1ELOVL1P4HTMASPH
SCHEMBL15639717 0.76 ELOVL1 (0.35) KDM4EELOVL1ALBPLAUELANE
SCHEMBL15577160 0.76 ADAMTS7 (0.49) KDM4EELOVL1MAPK14HDAC1ADAMTS7
SCHEMBL1752087 0.75 P2RX7 (0.53) KDM4ETSHRELOVL1HDAC1ADAMTS7
SCHEMBL2327827 0.75 KMT2A (0.47) KDM4EELOVL1P4HTMMAPK14HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11548854-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2023-01-10 — — US disclosed
US-11332448-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2022-05-17 — — US disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 — — CN disclosed
US-10961201-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2021-03-30 — — US disclosed
US-10961201-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2021-03-30 — — US disclosed
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-02-25 — — US disclosed
EP-3125692-B1 USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES BAYER CROPSCIENCE AG (DE) 2021-01-27 — — EP disclosed
EP-3125692-B1 USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES BAYER CROPSCIENCE AG (DE) 2021-01-27 — — EP disclosed
US-20210017136-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-01-21 — — US disclosed
US-20210017136-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2021-01-21 — — US disclosed
WO-2015150252-A1 USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES BAYER CROPSCIENCE AG (DE) 2015-10-08 — — WO disclosed
WO-2015150252-A1 USE OF HETEROCYCLIC COMPOUNDS FOR CONTROLLING NEMATODES BAYER CROPSCIENCE AG (DE) 2015-10-08 — — WO disclosed
WO-2015144683-A1 INSECTICIDAL AND NEMATOCIDAL ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2015-10-01 — — WO disclosed
WO-2015144683-A1 INSECTICIDAL AND NEMATOCIDAL ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AG (DE) 2015-10-01 — — WO disclosed
WO-2015144652-A2 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF UNWANTED MICROORGANISMS BAYER CROPSCIENCE AG (DE) 2015-10-01 — — WO disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2015-08-27 — — US disclosed
EP-2903440-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer CropScience AG (DE) 2015-08-12 — — EP disclosed
WO-2014053450-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2014-04-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10961201-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS KDM4E 1583/4885ALOX15 2253/4885TSHR 2486/4885
US-11548854-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS KDM4E 1583/4885ALOX15 2253/4885TSHR 2486/4885
US-20210053924-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS KDM4E 1583/4885ALOX15 2253/4885TSHR 2486/4885
US-11332448-B2 Heterocyclic compounds as pesticides DDT, ACHE, PTMS KDM4E 1583/4885ALOX15 2253/4885TSHR 2486/4885
US-20210017136-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS KDM4E 1583/4885ALOX15 2253/4885TSHR 2486/4885
US-20150239847-A1 HETEROCYCLIC COMPOUNDS AS PESTICIDES DDT, ACHE, PTMS KDM4E 1583/4885ALOX15 2253/4885TSHR 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.