Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29814973 | 0.83 | PKM (0.53) | P2RX7PKMMAPTTSHR | |
| SCHEMBL909444 | 0.83 | PKM (0.53) | P2RX7PKMMAPTTSHR | |
| SCHEMBL1345638 | 0.81 | P2RX7 (0.45) | P2RX7PKMIDO1AGXT | |
| SCHEMBL1344059 | 0.81 | P2RX7 (0.45) | P2RX7PKMMAOBCYP3A4MAPT | |
| SCHEMBL1699443 | 0.81 | MAOB (0.51) | P2RX7PKMMAOBIDO1AGXT | |
| SCHEMBL30883124 | 0.81 | P2RX7 (0.45) | P2RX7PKML3MBTL1F2RALDH1A1 | |
| SCHEMBL909006 | 0.81 | P2RX7 (0.45) | P2RX7PKML3MBTL1F2RALDH1A1 | |
| SCHEMBL14232910 | 0.79 | P2RX7 (0.45) | P2RX7MAOBCYP3A4L3MBTL1MAPT | |
| SCHEMBL12819675 | 0.79 | SRC (0.42) | CYP3A4L3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL16155664 | 0.79 | PKM (0.41) | P2RX7PKMMAPTIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590340-B1 | INTERMEDIATES FOR THE SYNTHESIS OF FUNGICIDAL PYRAZOLES | FMC CORP (US) | 2023-11-15 | — | — | EP | claimed |
| US-20170260142-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | DU PONT (US) | 2017-09-14 | — | — | US | claimed |
| US-9688639-B2 | Solid forms of fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-06-27 | — | — | US | claimed |
| EP-2999695-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | E. I. du Pont de Nemours and Company (US) | 2016-03-30 | — | — | EP | claimed |
| US-20160075661-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-03-17 | — | — | US | claimed |
| EP-3590340-B1 | INTERMEDIATES FOR THE SYNTHESIS OF FUNGICIDAL PYRAZOLES | FMC CORP (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20180310562-A1 | FUNGICIDAL PYRAZOLE MIXTURES | FMC CORP (US) | 2018-11-01 | — | — | US | disclosed |
| US-10015966-B2 | Fungicidal pyrazole mixtures | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-07-10 | — | — | US | disclosed |
| US-20170260142-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | DU PONT (US) | 2017-09-14 | — | — | US | disclosed |
| US-20170260142-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | DU PONT (US) | 2017-09-14 | — | — | US | disclosed |
| US-20170260142-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | DU PONT (US) | 2017-09-14 | — | — | US | disclosed |
| EP-2809157-B1 | FUNGICIDAL PYRAZOLE MIXTURES | DU PONT (US) | 2017-09-06 | — | — | EP | disclosed |
| WO-2014130409-A2 | FUNGICIDAL PYRAZOLE MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-28 | — | — | WO | disclosed |
| WO-2013116251-A2 | FUNGICIDAL PYRAZOLE MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-08-08 | — | — | WO | disclosed |
| EP-2611296-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2012031061-A2 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
| CN-1090617-C | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 2002-09-11 | — | — | CN | disclosed |
| CN-1349796-A | Pyrrole derivatives and medicine composition | NIPPON SHINYAKU CO LTD (JP) | 2002-05-22 | — | — | CN | disclosed |
| CN-1186485-A | Pyrrole derivatives and pharmaceutical compositions | NIPPON SHINYAKU CO LTD (JP) | 1998-07-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130129839-A1 | FUNGICIDAL PYRAZOLES AND THEIR MIXTURES | CYP1B1, NOX3, NOX1 | P2RX7 710/4885PKM 1529/4885MAOB 429/4885 |
| US-20170260142-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | NOD1, AFF1, MAST1 | P2RX7 2231/4885PKM 3343/4885MAOB 2686/4885 |
| US-10015966-B2 | Fungicidal pyrazole mixtures | CYP1B1, CBR3, CBR1 | P2RX7 2076/4885PKM 2523/4885MAOB 157/4885 |
| US-20160075661-A1 | SOLID FORMS OF FUNGICIDAL PYRAZOLES | NOD1, AFF1, MAST1 | P2RX7 2231/4885PKM 3343/4885MAOB 2686/4885 |
| US-20180310562-A1 | FUNGICIDAL PYRAZOLE MIXTURES | CYP1B1, CBR3, CBR1 | P2RX7 2076/4885PKM 2523/4885MAOB 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.