Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573149 | 0.93 | PTGES (0.40) | ITGB3ITGAVKMT2APTGESALOX5 | |
| SCHEMBL1573270 | 0.91 | KMT2A (0.38) | KMT2APTGESALOX5PPARGPPARA | |
| SCHEMBL1573428 | 0.85 | APAF1 (0.42) | KMT2ASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL1574142 | 0.83 | SMN1; SMN2 (0.37) | KMT2ASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL697528 | 0.83 | IDH1 (0.34) | KMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL698793 | 0.80 | KMT2A (0.50) | KMT2AALDH1A1MAPTMEN1TDP1 | |
| SCHEMBL698574 | 0.80 | KMT2A (0.50) | KMT2AALDH1A1MAPTMEN1TDP1 | |
| SCHEMBL696323 | 0.77 | SMN1; SMN2 (0.38) | KMT2ASMN1; SMN2ALDH1A1MAPTMEN1 | |
| SCHEMBL4008767 | 0.77 | SMN1; SMN2 (0.43) | KMT2ASMN1; SMN2ALDH1A1MAPTFPR2 | |
| SCHEMBL4014276 | 0.76 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2ALDH1A1FPR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | claimed |
| US-7547718-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-16 | — | — | US | claimed |