Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | USP19 | O94966 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573270 | 0.84 | KMT2A (0.38) | SMN1; SMN2KMT2AMEN1LMNAGRIN2B | |
| SCHEMBL1573396 | 0.83 | ITGB3 (0.37) | SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL1573428 | 0.81 | APAF1 (0.42) | SMN1; SMN2KMT2AMEN1LMNATSHR | |
| SCHEMBL697530 | 0.80 | PTGS2 (0.37) | IDH1SMN1; SMN2 | |
| SCHEMBL1573149 | 0.80 | PTGES (0.40) | SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1574142 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2KMT2AMEN1TSHRGRIN2B | |
| SCHEMBL697529 | 0.77 | KLK7 (0.37) | OPRD1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL696942 | 0.76 | LDHA (0.38) | KMT2AMEN1TSHRLDHAGRIN2B | |
| SCHEMBL695810 | 0.74 | GUCY1B2 (0.36) | IDH1OPRD1KMT2AMEN1NPC1 | |
| SCHEMBL696567 | 0.74 | IDH1 (0.42) | IDH1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | claimed |
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |