Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15744765 | 0.92 | APP (0.42) | WDR5APPGRM5ACHEALDH1A1 | |
| SCHEMBL15744764 | 0.92 | APP (0.42) | WDR5APPGRM5ACHEALDH1A1 | |
| SCHEMBL2602434 | 0.84 | ACHE (0.48) | WDR5ACHEALDH1A1LMNACA1 | |
| SCHEMBL25590573 | 0.79 | ENPP2 (0.41) | APPCA1CA2TSHR | |
| SCHEMBL15744763 | 0.78 | ACHE (0.42) | WDR5ACHEALDH1A1LMNACA1 | |
| SCHEMBL5012559 | 0.77 | ALDH1A1 (0.52) | GRM5ACHEALDH1A1CYP2A6LMNA | |
| SCHEMBL14477632 | 0.72 | MEN1 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL25590575 | 0.70 | ENPP2 (0.44) | APPCA1CA2FFAR1TSHR | |
| SCHEMBL25491841 | 0.70 | PRSS1 (0.55) | ALDH1A1LMNA | |
| SCHEMBL5946335 | 0.70 | CA2 (0.46) | ALDH1A1CYP2A6LMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |