Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22633981 | 0.87 | PTGS2 (0.38) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL22634002 | 0.84 | KIF11 (0.39) | ALDH1A1PTGS2CYP3A4CYP2C19PTPN5 | |
| SCHEMBL28428404 | 0.82 | CHRM3 (0.37) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL7572691 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL28431550 | 0.78 | FABP4 (0.39) | ALDH1A1CYP3A4PTPN5PTPN2 | |
| SCHEMBL30219864 | 0.76 | HTR6 (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29559258 | 0.76 | HPGD (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL3238343 | 0.76 | MEN1 (0.42) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL22156237 | 0.75 | MAPT (0.37) | ALDH1A1KMT2ANPSR1SMN1; SMN2LMNA | |
| SCHEMBL18486592 | 0.75 | NPC1 (0.46) | MEN1KMT2ASMN1; SMN2LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212843-A | Boronic acid derivatives and synthesis thereof | QPEX生物制药有限公司 | 2020-05-29 | — | — | CN | claimed |
| CN-111417627-B | Hydrogenation of Imines Using RU Complexes | 弗门尼舍有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117616032-A | Rare earth complex | 东曹株式会社 | 2024-02-27 | — | — | CN | disclosed |
| CN-115260057-B | Improved method for preparing functionalized cis-trans dicyanoethylene compound through desulfurization of 2, 5-dinitrothiophene | 中国科学院大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-111406059-B | Europium complexes | 东曹株式会社 | 2023-04-18 | — | — | CN | disclosed |
| US-10988494-B2 | Europium complex | TOSOH CORPORATION (JP) | 2021-04-27 | — | — | US | disclosed |
| US-20200354389-A1 | EUROPIUM COMPLEX | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2020-11-12 | — | — | US | disclosed |
| CN-111406059-A | Europium complexes | 东曹株式会社 | 2020-07-10 | — | — | CN | disclosed |
| CN-111212843-A | Boronic acid derivatives and synthesis thereof | QPEX生物制药有限公司 | 2020-05-29 | — | — | CN | disclosed |
| CN-106103441-B | Spiro-compound, luminescent material and organic electroluminescence device with azepine fluorenes ring structure | 保土谷化学工业株式会社 | 2019-03-26 | — | — | CN | disclosed |
| WO-2005113536-A2 | TRI- AND BI-CYCLIC HETEROARYL HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005113551-A1 | BICYCLIC-SUBSTITUTED AMINES HAVING CYCLIC-SUBSTITUTED MONOCYCLIC SUBSTITUENTS | ABBOTT LABORATORIES (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050256309-A1 | Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands | ABBOTT LABORATORIES | 2005-11-17 | — | — | US | disclosed |
| US-20050256118-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | ABBOTT LABORATORIES | 2005-11-17 | — | — | US | disclosed |
| US-20050234031-A1 | Amino-substituted tricyclic derivatives and methods of use | ABBVIE INC. | 2005-10-20 | — | — | US | disclosed |
| EP-1569637-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | Abbott Laboratories (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2005077899-A2 | AMINO-SUBSTITUTED TRICYCLIC DERIVATIVES AND METHODS OF USE | ABBOTT LABORATORIES (US) | 2005-08-25 | — | — | WO | disclosed |
| US-20040152704-A1 | Bicyclic-substituted amines as histamine-3 receptor ligands | ABBVIE INC. | 2004-08-05 | — | — | US | disclosed |
| WO-2004043458-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20040092521-A1 | Bicyclic-substituted amines as histamine-3 receptor ligands | ABBOTT LABORATORIES | 2004-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234031-A1 | Amino-substituted tricyclic derivatives and methods of use | CHRNA1, CHRM1, GALR1 | ALDH1A1 1267/4885MEN1 2511/4885KMT2A 2287/4885 |
| US-20050256118-A1 | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents | HRH3, HRH4, HRH2 | ALDH1A1 2284/4885MEN1 1142/4885KMT2A 523/4885 |
| US-10988494-B2 | Europium complex | SSB, XPA, UACA | ALDH1A1 3892/4885MEN1 2354/4885KMT2A 3564/4885 |
| US-20050256309-A1 | Tri-and bi-cyclic heteroaryl histamine-3 receptor ligands | HRH3, HRH4, HRH2 | ALDH1A1 3121/4885MEN1 1776/4885KMT2A 785/4885 |
| US-20200354389-A1 | EUROPIUM COMPLEX | SSB, XPA, UACA | ALDH1A1 3892/4885MEN1 2354/4885KMT2A 3564/4885 |
| US-20040092521-A1 | Bicyclic-substituted amines as histamine-3 receptor ligands | HRH3, HRH4, HRH1 | ALDH1A1 698/4885MEN1 919/4885KMT2A 1805/4885 |
| US-20040152704-A1 | Bicyclic-substituted amines as histamine-3 receptor ligands | HRH3, HRH4, HRH1 | ALDH1A1 687/4885MEN1 711/4885KMT2A 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.