Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490265 | 0.86 | ATM (0.50) | ITGA4ITGB7CA12CA1CA7 | |
| SCHEMBL2490263 | 0.86 | ATM (0.50) | ITGA4ITGB7CA12CA1CA7 | |
| SCHEMBL224862 | 0.84 | CA12 (0.57) | CA12CA1CA7CA14CA2 | |
| SCHEMBL15671411 | 0.84 | CA12 (0.57) | CA12CA1CA7CA14CA2 | |
| SCHEMBL8843234 | 0.81 | RIPK1 (0.43) | RIPK1CTSLCTSSTLR2 | |
| SCHEMBL27896404 | 0.81 | MEN1 (0.48) | POLBMAPTL3MBTL1CTSLCTSS | |
| SCHEMBL1576807 | 0.79 | FOLH1 (0.49) | CA1CA7CA2CA9 | |
| SCHEMBL30673429 | 0.79 | MMP2 (0.41) | CA12CA1CA7CA14CA2 | |
| SCHEMBL9299480 | 0.79 | CTSK (0.59) | CTSLCTSSCTSK | |
| SCHEMBL19450068 | 0.79 | POLB (0.51) | POLBTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853439-B2 | Processes for the preparation of lacosamide and intermediates thereof | CADILA HEALTHCARE LIMITED (IN) | 2014-10-07 | — | — | US | claimed |
| US-20120209022-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2012-08-16 | — | — | US | claimed |
| EP-2480524-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | Cadila Healthcare Limited (IN) | 2012-08-01 | — | — | EP | claimed |
| WO-2011039781-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2011-04-07 | — | — | WO | claimed |
| US-9242926-B2 | Processes for the preparation of lacosamide and intermediates thereof | CADILA HEALTHCARE LIMITED (IN) | 2016-01-26 | — | — | US | disclosed |
| US-8853439-B2 | Processes for the preparation of lacosamide and intermediates thereof | CADILA HEALTHCARE LIMITED (IN) | 2014-10-07 | — | — | US | disclosed |
| US-20140296572-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2014-10-02 | — | — | US | disclosed |
| US-20120209022-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2012-08-16 | — | — | US | disclosed |
| EP-2480524-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | Cadila Healthcare Limited (IN) | 2012-08-01 | — | — | EP | disclosed |
| WO-2011039781-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120209022-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CA3, TREH, NAAA | ITGA4 4619/4885ITGB7 4599/4885CA12 31/4885 |
| US-20140296572-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CA3, TREH, NAAA | ITGA4 4619/4885ITGB7 4599/4885CA12 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.