Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775094 | 0.88 | KEAP1 (0.38) | KEAP1NFE2L2HDAC8ALDH1A1GPR119 | |
| SCHEMBL28779145 | 0.83 | CHRM2 (0.42) | KEAP1NFE2L2HDAC8ALDH1A1EPHX2 | |
| SCHEMBL15347416 | 0.81 | SLC6A9 (0.43) | ALDH1A1EPHX2GPR119MEN1KMT2A | |
| SCHEMBL1673065 | 0.81 | SLC6A9 (0.43) | ALDH1A1EPHX2GPR119MEN1KMT2A | |
| SCHEMBL23235715 | 0.79 | SLC6A9 (0.44) | ALDH1A1GPR119MEN1KMT2A | |
| SCHEMBL13812253 | 0.79 | SLC6A9 (0.44) | ALDH1A1GPR119MEN1KMT2A | |
| SCHEMBL18502954 | 0.75 | ALDH1A1 (0.39) | ALDH1A1EPHX2RAB9AGPR119MEN1 | |
| SCHEMBL3319602 | 0.75 | NR1H2 (0.40) | ALDH1A1EPHX2GPR119MEN1KMT2A | |
| SCHEMBL3315088 | 0.75 | NR1H2 (0.40) | ALDH1A1EPHX2GPR119MEN1KMT2A | |
| SCHEMBL3179712 | 0.73 | NR1H2 (0.41) | ALDH1A1EPHX2GPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078095-A1 | NEUROTENSIN RECEPTOR LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2026-03-19 | — | — | US | disclosed |
| EP-3712131-B1 | NEUROTENSIN RECEPTOR LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2023-02-01 | — | — | EP | disclosed |
| US-10961199-B2 | Neurotensin receptor ligands | 3B PHARMACEUTICALS GMBH (DE) | 2021-03-30 | — | — | US | disclosed |
| US-20210087149-A1 | NEUROTENSIN RECEPTOR LIGANDS | 3B Pharmaceuticals (DE) | 2021-03-25 | — | — | US | disclosed |
| US-10799605-B2 | Conjugate comprising a neurotensin receptor ligand and use thereof | 3B PHARMACEUTICALS GMBH (DE) | 2020-10-13 | — | — | US | disclosed |
| EP-3712131-A1 | NEUROTENSIN RECEPTOR LIGANDS | 3B Pharmaceuticals GmbH (DE) | 2020-09-23 | — | — | EP | disclosed |
| EP-2928870-B1 | NEUROTENSIN RECEPTOR LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2020-04-08 | — | — | EP | disclosed |
| US-20170119913-A1 | CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2017-05-04 | — | — | US | disclosed |
| EP-3154638-A1 | CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF | 3B Pharmaceuticals GmbH (DE) | 2017-04-19 | — | — | EP | disclosed |
| WO-2015188934-A1 | CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2015-12-17 | — | — | WO | disclosed |
| EP-2954934-A1 | Conjugate comprising a neurotensin receptor ligand and use thereof | 3B Pharmaceuticals GmbH (DE) | 2015-12-16 | — | — | EP | disclosed |
| US-20150299133-A1 | NEUROTENSIN RECEPTOR LIGANDS | 3 B Pharmaceuticals GmbH | 2015-10-22 | — | — | US | disclosed |
| EP-2928870-A1 | NEUROTENSIN RECEPTOR LIGANDS | 3B Pharmaceuticals GmbH (DE) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014086499-A1 | NEUROTENSIN RECEPTOR LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2014-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087149-A1 | NEUROTENSIN RECEPTOR LIGANDS | NTSR1, NTSR2, TACR3 | KEAP1 2604/4885NFE2L2 4199/4885HDAC8 2968/4885 |
| US-20150299133-A1 | NEUROTENSIN RECEPTOR LIGANDS | NTSR1, NTSR2, TACR3 | KEAP1 2570/4885NFE2L2 4217/4885HDAC8 3136/4885 |
| US-20170119913-A1 | CONJUGATE COMPRISING A NEUROTENSIN RECEPTOR LIGAND AND USE THEREOF | NTSR1, NTSR2, ADGRF1 | KEAP1 2484/4885NFE2L2 4252/4885HDAC8 2813/4885 |
| US-10799605-B2 | Conjugate comprising a neurotensin receptor ligand and use thereof | NTSR1, NTSR2, TAAR1 | KEAP1 2520/4885NFE2L2 4232/4885HDAC8 2802/4885 |
| US-10961199-B2 | Neurotensin receptor ligands | NTSR1, NTSR2, TACR3 | KEAP1 2570/4885NFE2L2 4217/4885HDAC8 3136/4885 |
| US-20260078095-A1 | NEUROTENSIN RECEPTOR LIGANDS | NTSR1, NTSR2, GRPR | KEAP1 3800/4885NFE2L2 4513/4885HDAC8 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.