Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775665 | 0.87 | ALDH1A1 (0.40) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL15775398 | 0.85 | RAB9A (0.40) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL15775407 | 0.85 | CCNE2 (0.44) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL15775431 | 0.84 | NOTUM (0.38) | RAB9ANPC1MAPTKDM4ESMN1; SMN2 | |
| Bromide SCHEMBL15775833 | 0.84 | RXFP1 (0.34) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| Bromide SCHEMBL15775323 | 0.84 | TYR (0.41) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL15775290 | 0.83 | RAB9A (0.38) | RAB9ANPC1MAPTALDH1A1KDM4E | |
| SCHEMBL15775980 | 0.82 | LAP3 (0.41) | PARP1 | |
| Bromide SCHEMBL15775523 | 0.81 | LAP3 (0.40) | PARP1 | |
| SCHEMBL15775204 | 0.81 | CYP19A1 (0.41) | RAB9ANPC1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |