Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15775416 | 0.86 | ADORA1 (0.43) | NPC1MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL15775739 | 0.85 | TNKS (0.40) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL15775366 | 0.85 | RAB9A (0.38) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL15775756 | 0.84 | ALDH1A1 (0.42) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| SCHEMBL15775665 | 0.83 | ALDH1A1 (0.40) | NPC1RAB9AMAPTSMN1; SMN2PARP1 | |
| Bromide SCHEMBL15775323 | 0.81 | TYR (0.41) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL15775431 | 0.81 | NOTUM (0.38) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| Bromide SCHEMBL15775833 | 0.81 | RXFP1 (0.34) | NPC1RAB9AMAPTSMN1; SMN2PARP1 | |
| SCHEMBL15775318 | 0.80 | HTR7 (0.42) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15775307 | 0.80 | UGCG (0.41) | RAB9AMAPTSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |