Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | IL1RN | P18510 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775366 | 0.87 | RAB9A (0.38) | ALDH1A1PARP1RAB9ASMN1; SMN2KDM4E | |
| Bromide SCHEMBL15775273 | 0.87 | MAOA (0.35) | ALDH1A1PARP1MAPT | |
| Bromide SCHEMBL15775833 | 0.85 | RXFP1 (0.34) | ALDH1A1HSD17B10PARP1RAB9ASMN1; SMN2 | |
| Bromide SCHEMBL15775323 | 0.85 | TYR (0.41) | ALDH1A1HSD17B10PARP1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15775431 | 0.85 | NOTUM (0.38) | PARP1RAB9ASMN1; SMN2KDM4ENPC1 | |
| Bromide SCHEMBL15775614 | 0.83 | GRM2 (0.40) | KDM4EADORA2AADORA1MAPTDHFR | |
| SCHEMBL15775980 | 0.83 | LAP3 (0.41) | PARP1 | |
| SCHEMBL15775407 | 0.83 | CCNE2 (0.44) | ALDH1A1PARP1RAB9ASMN1; SMN2KDM4E | |
| Bromide SCHEMBL15775523 | 0.82 | LAP3 (0.40) | PARP1 | |
| SCHEMBL15775298 | 0.81 | ALDH1A1 (0.38) | ALDH1A1AXLRAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |