Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | FGB | P02675 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15775497 | 0.99 | UGCG (0.40) | UGCGALDH1A1ADRA2BPTGS1TDP1 | |
| SCHEMBL15775407 | 0.80 | CCNE2 (0.44) | ALDH1A1TDP1PDCD1CD274MAPT | |
| SCHEMBL4763654 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TDP1PDCD1CD274MEN1 | |
| SCHEMBL15775665 | 0.79 | ALDH1A1 (0.40) | ALDH1A1ADORA2AADORA1MAPTRAB9A | |
| Bromide SCHEMBL15776793 | 0.78 | BCHE (0.35) | ALDH1A1ADORA2AMEN1POLBMAPT | |
| SCHEMBL15775346 | 0.78 | ACHE (0.43) | UGCGALDH1A1ACHEMAPTRAB9A | |
| Bromide SCHEMBL15775416 | 0.77 | ADORA1 (0.43) | ALDH1A1ADORA2AADORA1MEN1POLB | |
| SCHEMBL15775366 | 0.75 | RAB9A (0.38) | ALDH1A1CD274ADORA2AMEN1MAPT | |
| Bromide SCHEMBL15775650 | 0.75 | NOTUM (0.35) | — | |
| Bromide SCHEMBL15775833 | 0.74 | RXFP1 (0.34) | ALDH1A1PTGS1ADORA2AADORA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |