Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.46 |
| ▸ | NOS1 | P29475 | 9/20 | 0.39 |
| ▸ | NOS2 | P35228 | 5/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15820887 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TRPA1TSHRCHRNA7NOS1 | |
| SCHEMBL31396820 | 0.94 | ALDH1A1 (0.52) | ALDH1A1TRPA1TSHRCHRNA7NOS1 | |
| SCHEMBL8439706 | 0.82 | TRPA1 (0.42) | ALDH1A1TRPA1TSHRCHRNA7NOS1 | |
| SCHEMBL347355 | 0.81 | MIF (0.48) | ALDH1A1TRPA1TSHRCHRNA7NOS1 | |
| SCHEMBL348159 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TRPA1TSHRNOS1NOS2 | |
| SCHEMBL2213709 | 0.79 | ALDH1A1 (0.61) | ALDH1A1TRPA1TSHRNOS1NOS2 | |
| SCHEMBL23270659 | 0.77 | HTR1A (0.40) | ALDH1A1TRPA1TSHRNOS1NOS2 | |
| SCHEMBL9362872 | 0.76 | NOS1 (0.56) | TSHRCHRNA7NOS1NOS2NOS3 | |
| SCHEMBL24422635 | 0.76 | NOS1 (0.62) | NOS1NOS2NOS3 | |
| SCHEMBL17707286 | 0.76 | SIGMAR1 (0.50) | CHRNA7NOS1NOS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935252-A1 | NOVEL BIS-CHROMONE DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF | Rijksuniversiteit te Groningen (NL) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014098597-A1 | NOVEL BIS-CHROMONE DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2014-06-26 | — | — | WO | disclosed |