Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | MC4R | P32245 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15808875 | 0.84 | MMP2 (0.40) | MMP2ADAM17SRCALOX15ALDH1A1 | |
| SCHEMBL15822166 | 0.82 | ALOX15 (0.45) | MMP2ADAM17MC4RCYP1A2CYP3A4 | |
| SCHEMBL29390329 | 0.82 | ALOX15 (0.45) | MMP2ADAM17MC4RCYP1A2CYP3A4 | |
| SCHEMBL18009548 | 0.75 | TSHR (0.42) | CYP3A4ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL233314 | 0.74 | TAAR1 (0.41) | SRCCYP1A2CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL8577196 | 0.72 | CYP1A2 (0.42) | MMP2ADAM17CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL2486083 | 0.72 | ACACB (0.45) | MEN1KMT2APTGS2 | |
| SCHEMBL8142729 | 0.71 | AMY1A (0.38) | SRCGSK3BCYP1A2 | |
| SCHEMBL14645471 | 0.71 | FFAR4 (0.35) | MMP2ADAM17ALDH1A1MAPTMEN1 | |
| SCHEMBL2485263 | 0.71 | PPARA (0.42) | CYP1A2CYP3A4CYP2D6ALOX15CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469699-B2 | Catalysts | BOREALIS AG (AT) | 2016-10-18 | — | — | US | disclosed |
| US-9469699-B2 | Catalysts | BOREALIS AG (AT) | 2016-10-18 | — | — | US | disclosed |
| US-20160002369-A1 | CATALYSTS | BOREALIS AG (AT) | 2016-01-07 | — | — | US | disclosed |
| US-20160002369-A1 | CATALYSTS | BOREALIS AG (AT) | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002369-A1 | CATALYSTS | SIGMAR1, SFN, AP3S1 | MMP2 3258/4885ADAM17 4532/4885SRC 226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.