SCHEMBL15828633

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11869664	0.85	ALDH1A1 (0.50)	CYP3A4NAMPTXDHALDH1A1PARP1
	SCHEMBL9959976	0.76	CYP3A4 (0.42)	CYP3A4NAMPTXDHGPR35ALDH1A1
	SCHEMBL20801721	0.76	CYP3A4 (0.40)	CYP3A4NAMPTXDHALDH1A1PARP1
	SCHEMBL15756184	0.75	POLB (0.38)	CYP3A4ALDH1A1PARP1MAPK1PDPK1
	SCHEMBL30665177	0.73	CYP3A4 (0.40)	CYP3A4NAMPTXDHPARP1NPC1
	SCHEMBL15828618	0.73	MAPT (0.53)	CYP3A4GPR35ALDH1A1NPC1RAB9A
	SCHEMBL15756185	0.72	MAPT (0.36)	PARP1PDPK1MAPT
	SCHEMBL15828639	0.72	MAPT (0.36)	XDHALDH1A1PARP1NPC1RAB9A
	SCHEMBL2990287	0.72	CA2 (0.51)	CYP3A4NAMPTXDHALDH1A1PARP1
	SCHEMBL26938392	0.70	GPR35 (0.39)	CYP3A4GPR35ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.