Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828633 | 0.76 | CYP3A4 (0.40) | CYP3A4NAMPTXDHPARP1EP300 | |
| SCHEMBL11869664 | 0.76 | ALDH1A1 (0.50) | CYP3A4NAMPTXDHPARP1MAPT | |
| SCHEMBL20801721 | 0.76 | CYP3A4 (0.40) | CYP3A4NAMPTXDHPARP1FBP1 | |
| SCHEMBL30665177 | 0.76 | CYP3A4 (0.40) | CYP3A4NAMPTXDHPARP1EP300 | |
| SCHEMBL2990287 | 0.75 | CA2 (0.51) | CYP3A4NAMPTXDHPARP1MAPT | |
| SCHEMBL18152655 | 0.73 | MEN1 (0.49) | CYP3A4NAMPTXDHAKR1B1ERN1 | |
| SCHEMBL27627269 | 0.73 | AKR1B1 (0.42) | CYP3A4AKR1B1ERN1FBP1MAPT | |
| SCHEMBL311328 | 0.72 | TXNRD1 (0.49) | CYP3A4NAMPTXDHPARP1MAPT | |
| SCHEMBL12473103 | 0.72 | GRIN2D (0.40) | AKR1B1ERN1FBP1MAPTMEN1 | |
| SCHEMBL25174769 | 0.70 | NOS1 (0.57) | CYP3A4AKR1B1ERN1FBP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120092010-A | Polycyclic poly (ADP-ribose) polymerase selective inhibitors | 轩竹生物科技股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |