Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16879764 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4EMEN1KMT2AADORA1 | |
| SCHEMBL15832018 | 0.82 | ADORA2A (0.42) | ALDH1A1KDM4EMEN1KMT2AADORA1 | |
| SCHEMBL15832017 | 0.80 | KDM4E (0.48) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL15832006 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL15832007 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2AADORA1 | |
| SCHEMBL15832003 | 0.80 | ADORA1 (0.51) | ALDH1A1KDM4EADORA1HPGDMAPT | |
| SCHEMBL2528908 | 0.79 | PGR (0.56) | ALDH1A1KDM4EMEN1KMT2AADORA1 | |
| SCHEMBL15832008 | 0.77 | KIF11 (0.47) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL28123958 | 0.76 | KIF11 (0.46) | CYP11B1CYP11B2ARCNR1 | |
| SCHEMBL4037256 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | GRUENENTHAL GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | TRPV1, TRPV5, TRPV2 | ALDH1A1 2444/4885KDM4E 4191/4885MEN1 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.