Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15832155 | 0.80 | SMN1; SMN2 (0.57) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL15832160 | 0.76 | PPIB (0.44) | GAAMEN1KMT2AALDH1A1ALOX12 | |
| SCHEMBL14617669 | 0.74 | SMN1; SMN2 (0.68) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL3343137 | 0.72 | ALOX12 (0.67) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL19373208 | 0.71 | ALDH1A1 (0.61) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL13719809 | 0.71 | NPC1 (0.67) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL15832162 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL19882171 | 0.69 | ALOX12 (0.48) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL16357663 | 0.69 | ADAM17 (0.58) | SMN1; SMN2GAAMEN1KMT2ANPC1 | |
| SCHEMBL29221795 | 0.69 | SMN1; SMN2 (0.66) | SMN1; SMN2GAAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | FKBP3, FKBP4, FKBP5 | SMN1; SMN2 2177/4885GAA 3558/4885MEN1 4127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.