SCHEMBL15836550

SCHEMBL15836550

CCN(CC)CCNC(=O)c1ccc2cc(NC(=O)ON3C(=O)CCC3=O)ccc2n1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.41
▸ TERT O14746 1/20 0.41
▸ MCHR1 Q99705 6/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ POLB P06746 2/20 0.40
▸ TP53 P04637 1/20 0.40
▸ NFKB1 P19838 1/20 0.40
▸ KCNH2 Q12809 1/20 0.40
▸ SCN9A Q15858 5/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ THRB P10828 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30028338 1.00 LMNA (0.41) LMNATERTMCHR1ALDH1A1SMN1; SMN2
SCHEMBL22295268 0.94 LMNA (0.40) LMNATERTMCHR1ALDH1A1SMN1; SMN2
SCHEMBL16261008 0.87 MCHR1 (0.39) MCHR1ALDH1A1SMN1; SMN2KMT2APOLB
SCHEMBL15836551 0.86 KMT2A (0.51) LMNAMCHR1ALDH1A1SMN1; SMN2KMT2A
SCHEMBL16261002 0.85 KMT2A (0.50) LMNAMCHR1ALDH1A1SMN1; SMN2KMT2A
SCHEMBL16261004 0.85 ALDH1A1 (0.41) LMNAALDH1A1SMN1; SMN2KDM4EKMT2A
SCHEMBL16260996 0.85 POLB (0.42) LMNAMCHR1ALDH1A1SMN1; SMN2KMT2A
SCHEMBL20024499 0.83 KMT2A (0.42) LMNATERTMCHR1ALDH1A1SMN1; SMN2
SCHEMBL16260991 0.82 TERT (0.44) TERTMCHR1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL25963271 0.82 TERT (0.44) TERTMCHR1ALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4033223-B1 METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME WATERS TECHNOLOGIES CORP (US) 2025-06-18 — — EP disclosed
US-12158472-B2 Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same WATERS TECHNOLOGIES CORPORATION (US) 2024-12-03 — — US disclosed
US-11747310-B2 Methods for liquid chromatography calibration for rapid labeled N-glycans WATERS TECHNOLOGIES CORPORATION (US) 2023-09-05 — — US disclosed
US-11747310-B2 Methods for liquid chromatography calibration for rapid labeled N-glycans WATERS TECHNOLOGIES CORPORATION (US) 2023-09-05 — — US disclosed
US-11747310-B2 Methods for liquid chromatography calibration for rapid labeled N-glycans WATERS TECHNOLOGIES CORPORATION (US) 2023-09-05 — — US disclosed
EP-4234062-A2 METHODS OF ELECTROSPRAY IONIZATION OF GLYCANS MODIFIED WITH AMPHIPATHIC, STRONGLY BASIC MOIETIES Waters Technologies Corporation (US) 2023-08-30 — — EP disclosed
EP-3744708-B1 CALIBRANT FOR LIQUID CHROMATOGRAPHY CALIBRATION OF LABELED N-GLYCANS WATERS TECHNOLOGIES CORP (US) 2023-08-09 — — EP disclosed
EP-3744708-B1 CALIBRANT FOR LIQUID CHROMATOGRAPHY CALIBRATION OF LABELED N-GLYCANS WATERS TECHNOLOGIES CORP (US) 2023-08-09 — — EP disclosed
CN-115260154-A Rapid fluorescent labeling of glycans and other biomolecules with enhanced MS signal 沃特世科技公司 2022-11-01 — — CN disclosed
US-20220268779-A1 METHODS FOR THE RAPID PREPARATION OF LABELED GLYCOSYLAMINES AND FOR THE ANALYSIS OF GLYCOSYLATED BIOMOLECULES PRODUCING THE SAME WATERS TECHNOLOGIES CORPORATION (US) 2022-08-25 — — US disclosed
US-9772333-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals WATER TECHNOLOGIES CORPORATION (US) 2017-09-26 — — US disclosed
WO-2016077548-A1 METHODS FOR LIQUID CHROMATOGRAPHY CALIBRATION FOR RAPID LABELED N-GLYCANS WATERS TECHNOLOGIES CORPORATION (US) 2016-05-19 — — WO disclosed
US-20160139136-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2016-05-19 — — US disclosed
US-20160139136-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2016-05-19 — — US disclosed
EP-2990401-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MASS SPECTROMETRY SIGNALS Waters Technologies Corporation (US) 2016-03-02 — — EP disclosed
US-20140350263-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2014-11-27 — — US disclosed
US-20140350263-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2014-11-27 — — US disclosed
US-20140242709-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2014-08-28 — — US disclosed
US-20140179011-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2014-06-26 — — US disclosed
US-20140179011-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2014-06-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140350263-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS FUT5, FUT6, CSGALNACT1 LMNA 1566/4885TERT 4768/4885MCHR1 2836/4885
US-11747310-B2 Methods for liquid chromatography calibration for rapid labeled N-glycans DDOST, STT3B, CSGALNACT1 LMNA 586/4885TERT 4240/4885MCHR1 2711/4885
US-20160139136-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS FUT5, FUT6, CSGALNACT1 LMNA 1566/4885TERT 4768/4885MCHR1 2836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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