Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216358 | 0.88 | — | — | |
| SCHEMBL3030818 | 0.87 | HTR2A (0.47) | MAOAMAOBHTR2ASMN1; SMN2SLC6A3 | |
| SCHEMBL6294089 | 0.87 | MAOA (0.48) | MAOAMAOBHTR2ASIGMAR1 | |
| SCHEMBL18917615 | 0.85 | SIGMAR1 (0.48) | MAOAMAOBSIGMAR1 | |
| SCHEMBL3028982 | 0.85 | SIGMAR1 (0.48) | MAOAMAOBSIGMAR1 | |
| SCHEMBL11553069 | 0.85 | SIGMAR1 (0.48) | MAOAMAOBSIGMAR1 | |
| SCHEMBL4405621 | 0.84 | ESR1 (0.54) | ALDH1A1TDP1TAAR1SIGMAR1 | |
| SCHEMBL1862280 | 0.84 | LOXL2 (0.42) | TDP1SMN1; SMN2LOXL2 | |
| SCHEMBL9320456 | 0.84 | KCNH2 (0.47) | ALDH1A1ALOX15KCNH2TDP1CYP2A6 | |
| SCHEMBL8094403 | 0.79 | KCNJ1 (0.46) | MAOAMAOBHPGDHSD17B10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966384-B1 | FRESHENING COMPOSITIONS WITH ALKOXYLATED PHENOLS | PROCTER & GAMBLE (US) | 2023-05-03 | — | — | EP | claimed |
| CN-106066578-B | Coloring composition, coloring cured film, color filter, display element and solid-state imaging element | JSR株式会社 | 2021-04-13 | — | — | CN | claimed |
| US-9233138-B2 | Compositions for promoting HIV-1 virolysis and methods using same | DREXEL UNIVERSITY (US) | 2016-01-12 | — | — | US | claimed |
| EP-1478335-B1 | PERFUME CONTAINING SURFACTANT COMPOSITIONS HAVING PERFUME BURST WHEN DILUTED AND PROCESS THEREOF | UNILEVER PLC (GB) | 2014-07-30 | — | — | EP | claimed |
| EP-2211829-B1 | IMPROVEMENT OF THE FRAGRANCE EFFECT OF PERFUME ESTERS | HENKEL AG & CO KGAA (DE) | 2011-04-27 | — | — | EP | claimed |
| CN-100494182-C | Regulatory factor of tumor necrosis alpha factor | GENZYME CORP (US) | 2009-06-03 | — | — | CN | claimed |
| US-7498460-B2 | Isophthalic acid derivatives | BAYER HEALTHCARE AG (DE) | 2009-03-03 | — | — | US | claimed |
| US-20080176898-A1 | Leukotriene antagonists; cardiovascular disorders like unstable angina pectoris or myocardial infarction; Methyl 1-{[5-(ethoxycarbonyl)-2-(3-{4-[(4-isopropoxybenzyl)oxy]phenyl}propoxy)phenyl]-acetyl}piperidine-4-carboxylate | BAYER HEALTHCARE AG (DE) | 2008-07-24 | — | — | US | claimed |
| EP-1290132-B1 | FABRIC CARE COMPOSITIONS AND SYSTEMS FOR DELIVERING CLEAN, FRESH SCENT IN A LIPOPHILIC FLUID TREATMENT PROCESS | PROCTER & GAMBLE (US) | 2008-04-30 | — | — | EP | claimed |
| EP-1572628-B1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-25 | — | — | EP | claimed |
| EP-1572628-A1 | ISOPHTALIC ACID DERIVATIVES | Bayer HealthCare AG (DE) | 2005-09-14 | — | — | EP | claimed |
| WO-2004052839-A1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-06-24 | — | — | WO | claimed |
| CN-1441787-A | Modulators of TNF-alpha signaling | GENZYME CORP (US) | 2003-09-10 | — | — | CN | claimed |
| EP-0787176-B1 | FABRIC SOFTENER COMPOSITIONS WITH REDUCED ENVIRONMENTAL IMPACT | PROCTER & GAMBLE (US) | 2003-05-07 | — | — | EP | claimed |
| WO-2001087842-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| EP-0535548-B1 | Inhibitor of atherosclerotic intimal thickening | NISSAN CHEMICAL IND LTD (JP) | 2001-11-21 | — | — | EP | claimed |
| EP-0404470-B1 | Fragrance compositions and their use in detergent products | QUEST INT (NL) | 1994-04-13 | — | — | EP | claimed |
| EP-0219308-B1 | 2-SUBSTITUTED QUINOLINES | MERCK FROSST CANADA INC. (CA) | 1991-10-23 | — | — | EP | claimed |
| EP-0147191-B1 | PERFUME AND COMPOSITIONS CONTAINING PERFUME | UNILEVER N.V. (NL) | 1989-10-04 | — | — | EP | claimed |
| US-3998802-A | POLYAMIDES, CELLULOSE ESTERS, POLYESTERS, POLYACRYLONITRILES | BASF AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176898-A1 | Leukotriene antagonists; cardiovascular disorders like unstable angina pectoris or myocardial infarction; Methyl 1-{[5-(ethoxycarbonyl)-2-(3-{4-[(4-isopropoxybenzyl)oxy]phenyl}propoxy)phenyl]-acetyl}piperidine-4-carboxylate | LTC4S, LTB4R2, LTB4R | MAOA 659/4885MAOB 484/4885ALDH1A1 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.