Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 2/20 | 0.52 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878268 | 0.93 | KDM4E (0.56) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL3876540 | 0.86 | EGFR (0.42) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL3886475 | 0.84 | MAPT (0.64) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL3874960 | 0.84 | AHR (0.59) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL26450313 | 0.79 | AHR (0.58) | KDM4EHPGDALDH1A1SMN1; SMN2AHR | |
| SCHEMBL26450328 | 0.79 | AHR (0.53) | KDM4EMAPTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL172890 | 0.78 | MAOA (0.54) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL15840239 | 0.78 | AHR (0.72) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL31192626 | 0.78 | AHR (0.52) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL25531245 | 0.78 | HPGD (0.56) | KDM4EMEN1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | GLENN ROBERT W JR | 2008-05-01 | — | — | US | claimed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | claimed |
| US-11877512-B2 | Organic electroluminescence device and compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2024-01-16 | — | — | US | disclosed |
| US-11877512-B2 | Organic electroluminescence device and compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2024-01-16 | — | — | US | disclosed |
| CN-115043852-B | Benzoxazole derivative and electroluminescent application thereof | 武汉天马微电子有限公司 | 2023-12-29 | — | — | CN | disclosed |
| US-20230139051-A1 | BENZOXAZOLE DERIVATIVE AND ELECTROLUMINESCENT APPLICATION THEREOF | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20230139051-A1 | BENZOXAZOLE DERIVATIVE AND ELECTROLUMINESCENT APPLICATION THEREOF | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-04 | — | — | US | disclosed |
| US-20230139051-A1 | BENZOXAZOLE DERIVATIVE AND ELECTROLUMINESCENT APPLICATION THEREOF | WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) | 2023-05-04 | — | — | US | disclosed |
| CN-115043852-A | Benzoxazole derivative and electroluminescent application thereof | 武汉天马微电子有限公司 | 2022-09-13 | — | — | CN | disclosed |
| US-20210098708-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-04-01 | — | — | US | disclosed |
| EP-3356355-B1 | COMPOUNDS AND COMBINATIONS FOR THE TREATMENT OF HIV | GILEAD SCIENCES INC (US) | 2020-05-13 | — | — | EP | disclosed |
| US-20060229303-A1 | Substituted quinobenzoxazine analogs | CYLENE PHARMACEUTICALS, INC. | 2006-10-12 | — | — | US | disclosed |
| WO-2006078317-A1 | SUBSTITUTED QUINOBENZOXAZINE ANALOGS AND METHODS OF USING THEREOF | CYLENE PHARMACEUTICALS, INC. (US) | 2006-07-27 | — | — | WO | disclosed |
| CN-1809572-A | Substituted quinobenzoxazine analogs | CYLENE PHARMACEUTICALS INC (US) | 2006-07-26 | — | — | CN | disclosed |
| US-20060029950-A1 | Substituted quinobenzoxazine analogs and methods of using thereof | CYLENE PHARMACEUTICALS, INC. | 2006-02-09 | — | — | US | disclosed |
| EP-1610759-A2 | SUBSTITUTED QUINOBENZOXAZINE ANALOGS | Cylene Pharmaceuticals, Inc. (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2005099656-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | disclosed |
| US-20050085468-A1 | Substituted quinobenzoxazine analogs | CYLENE PHARMACEUTICALS | 2005-04-21 | — | — | US | disclosed |
| WO-2004091504-A2 | SUBSTITUTED QUINOBENZOXAZINE ANALOGS | CYLENE PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | KDM4E 1549/4885MEN1 4857/4885MAPT 420/4885 |
| US-20050085468-A1 | Substituted quinobenzoxazine analogs | CYP3A5, UGT2B7, CYP2D6 | KDM4E 1205/4885MEN1 3714/4885MAPT 3632/4885 |
| US-20230139051-A1 | BENZOXAZOLE DERIVATIVE AND ELECTROLUMINESCENT APPLICATION THEREOF | TSPO, XDH, TARS2 | KDM4E 1209/4885MEN1 4735/4885MAPT 1395/4885 |
| US-11877512-B2 | Organic electroluminescence device and compound for organic electroluminescence device | LEF1, PIEZO1, L1CAM | KDM4E 1030/4885MEN1 1432/4885MAPT 2625/4885 |
| US-20060229303-A1 | Substituted quinobenzoxazine analogs | CYP3A5, UGT2B7, CYP2D6 | KDM4E 1205/4885MEN1 3714/4885MAPT 3632/4885 |
| US-20080098535-A1 | Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | KDM4E 1549/4885MEN1 4857/4885MAPT 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.