Sugi Predict

Sugi Predict / Compounds / SCHEMBL3886475

SCHEMBL3886475

SCHEMBL3886475

Nc1cc2oc3ccccc3c2cc1N

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.64
▸ KMT2A Q03164 5/20 0.64
▸ KDM4E B2RXH2 4/20 0.64
▸ ALDH1A1 P00352 4/20 0.64
▸ MEN1 O00255 4/20 0.64
▸ SMN1; SMN2 Q16637 4/20 0.64
▸ NPC1 O15118 4/20 0.64
▸ HPGD P15428 3/20 0.64
▸ RAB9A P51151 3/20 0.64
▸ AHR P35869 2/20 0.59
▸ NQO1 P15559 1/20 0.53
▸ TBK1 Q9UHD2 1/20 0.50
▸ MAOA P21397 3/20 0.47
▸ CYP1A2 P05177 2/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ GLA P06280 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ PGAM1 P18669 1/20 0.46
▸ CASP1 P29466 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25587812 0.84 HPGD (0.56) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL26631793 0.84 KMT2A (0.56) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL25531245 0.84 HPGD (0.56) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL3878268 0.84 KDM4E (0.56) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL15840239 0.84 AHR (0.72) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL3705973 0.84 KDM4E (0.56) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL16919496 0.84 AHR (0.71) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL571563 0.84 AHR (0.71) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL3876930 0.83 AHR (0.46) MAPTKMT2AKDM4EALDH1A1MEN1
SCHEMBL17196443 0.83 ALDH1A1 (0.55) MAPTKMT2AKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof GLENN ROBERT W JR 2008-05-01 — — US claimed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 — — US claimed
US-20230139809-A1 BENZIMIDAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2023-05-04 — — US disclosed
US-20230139809-A1 BENZIMIDAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2023-05-04 — — US disclosed
WO-2021151922-A1 BENZIMIDAZOLE DERIVATIVES MERCK PATENT GMBH (DE) 2021-08-05 — — WO disclosed
EP-2926385-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-08-05 — — EP disclosed
US-9273080-B2 Metal complexes MEREK PATENT GMBH (DE) 2016-03-01 — — US disclosed
US-9273080-B2 Metal complexes MEREK PATENT GMBH (DE) 2016-03-01 — — US disclosed
US-20150336959-A1 Electronic Device MERCK PATENT GMBH (DE) 2015-11-26 — — US disclosed
US-20150336959-A1 Electronic Device MERCK PATENT GMBH (DE) 2015-11-26 — — US disclosed
WO-2014082705-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2014-06-05 — — WO disclosed
US-20130082209-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2013-04-04 — — US disclosed
WO-2011157339-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2011-12-22 — — WO disclosed
US-7491245-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2009-02-17 — — US disclosed
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof GLENN ROBERT W JR 2008-05-01 — — US disclosed
US-7331997-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-02-19 — — US disclosed
EP-1735059-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2006-12-27 — — EP disclosed
WO-2005099656-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-10-27 — — WO disclosed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 — — US disclosed
US-3939194-A Bis-2-azomethine pigments, process for their manufacture and their use CIBA-GEIGY CORPORATION (US) 1976-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, CKMT1A; CKMT1B, TUBB6 MAPT 420/4885KMT2A 1681/4885KDM4E 1549/4885
US-20150336959-A1 Electronic Device ETFB, ETFA, XPOT MAPT 2133/4885KMT2A 2788/4885KDM4E 3240/4885
US-20230139809-A1 BENZIMIDAZOLE DERIVATIVES ECI1, COX4I1, BRD4 MAPT 2896/4885KMT2A 1225/4885KDM4E 763/4885
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof KRT18, CKMT1A; CKMT1B, TUBB6 MAPT 420/4885KMT2A 1681/4885KDM4E 1549/4885
US-20130082209-A1 METAL COMPLEXES MCOLN2, MCOLN1, AP1M1 MAPT 1164/4885KMT2A 2510/4885KDM4E 4129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.