Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.52 |
| ▸ | AMY2A | P04746 | 4/20 | 0.43 |
| ▸ | STAT3 | P40763 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15254624 | 0.89 | AMY1A (0.49) | AMY1AAMY2ASTAT3P4HBMEN1 | |
| SCHEMBL15845156 | 0.89 | AMY1A (0.49) | AMY1AAMY2ASTAT3P4HBMEN1 | |
| SCHEMBL3188633 | 0.87 | MEN1 (0.50) | AMY2AALDH1A1MEN1KMT2ALGALS8 | |
| SCHEMBL2139680 | 0.87 | MEN1 (0.50) | AMY2AALDH1A1MEN1KMT2ALGALS8 | |
| SCHEMBL6900928 | 0.87 | MEN1 (0.50) | AMY2AALDH1A1MEN1KMT2ALGALS8 | |
| SCHEMBL1389240 | 0.87 | MEN1 (0.50) | AMY2AALDH1A1MEN1KMT2ALGALS8 | |
| SCHEMBL2139671 | 0.87 | MEN1 (0.50) | AMY2AALDH1A1MEN1KMT2ALGALS8 | |
| SCHEMBL17580760 | 0.84 | AMY1A (0.52) | AMY1AAMY2ASTAT3GAAMGAM | |
| SCHEMBL15136505 | 0.84 | LGALS8 (0.53) | AMY1AAMY2AMEN1KMT2ALGALS8 | |
| SCHEMBL8529170 | 0.83 | AMY1A (0.39) | AMY1AAMY2ASTAT3PTGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9896711-B2 | Fluorogenic or fluorophoric compounds and uses thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160340709-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-11-24 | — | — | US | disclosed |
| US-9434975-B2 | Fluorogenic or fluorophoric compounds and uses thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-09-06 | — | — | US | disclosed |
| EP-2691383-B1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2015-01-21 | — | — | EP | disclosed |
| US-20140186878-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140186878-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | FDPS, FOS, PFKFB1 | AMY1A 2800/4885AMY2A 3313/4885STAT3 3797/4885 |
| US-20160340709-A1 | FLUOROGENIC OR FLUOROPHORIC COMPOUNDS AND USES THEREOF | FDPS, FOS, PFKFB1 | AMY1A 2800/4885AMY2A 3313/4885STAT3 3797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.