Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21563366 | 0.81 | HPGD (0.44) | ALDH1A1MAPTTSHR | |
| SCHEMBL12019255 | 0.79 | — | — | |
| SCHEMBL24461900 | 0.79 | CTSS (0.32) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL24533893 | 0.78 | ALDH1A1 (0.31) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL20882877 | 0.77 | ALDH1A1 (0.32) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5145085 | 0.77 | — | — | |
| SCHEMBL22622377 | 0.76 | CACNA1B (0.43) | ALDH1A1LMNAMAPT | |
| SCHEMBL22193426 | 0.76 | CACNA1B (0.43) | ALDH1A1LMNAMAPT | |
| SCHEMBL23071822 | 0.76 | — | — | |
| SCHEMBL1033955 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139490-B1 | DIAZO BICYCLIC SMAC MIMETICS AND THE USES THEREOF | UNIV MICHIGAN (US) | 2014-07-02 | — | — | EP | disclosed |