Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24533893 | 0.86 | ALDH1A1 (0.31) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL18291022 | 0.82 | LMNA (0.31) | CTSSCTSKALDH1A1LMNAMAPT | |
| SCHEMBL26542230 | 0.80 | FAAH (0.38) | ALDH1A1TSHR | |
| SCHEMBL18738973 | 0.79 | CTSS (0.36) | CTSSCTSK | |
| SCHEMBL15850486 | 0.79 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL21450612 | 0.78 | — | — | |
| SCHEMBL24799328 | 0.78 | — | — | |
| SCHEMBL19706422 | 0.78 | BACE1 (0.33) | CTSSCTSK | |
| SCHEMBL20862058 | 0.77 | TSHR (0.36) | CTSSCTSKALDH1A1LMNAMAPT | |
| SCHEMBL19387517 | 0.77 | ALDH1A1 (0.34) | ALDH1A1LMNAMAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022108992-A1 | PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA)-TARGETED PRODRUG FOR SELECTIVE KILLING OF CELLS EXPRESSING PSMA | THE JOHNS HOPKINS UNIVERSITY (US) | 2022-05-27 | — | — | WO | disclosed |