Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461900 | 0.86 | CTSS (0.32) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL15850486 | 0.78 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL5145085 | 0.77 | — | — | |
| SCHEMBL12019255 | 0.74 | — | — | |
| SCHEMBL22183413 | 0.73 | MEN1 (0.36) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL18291022 | 0.73 | LMNA (0.31) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL12848639 | 0.72 | FFAR2 (0.31) | — | |
| SCHEMBL22622377 | 0.72 | CACNA1B (0.43) | ALDH1A1LMNAMAPT | |
| SCHEMBL22193426 | 0.72 | CACNA1B (0.43) | ALDH1A1LMNAMAPT | |
| SCHEMBL23071822 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133069-A1 | PEPTIDOMIMETIC MATRIPTASE 2 INHIBITORS AND USES THEREOF | DISC MEDICINE, INC. (US) | 2022-06-23 | — | — | WO | disclosed |