Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.61 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10061592 | 1.00 | RIPK1 (0.61) | RIPK1RORCABCB1GPR119MEN1 | |
| SCHEMBL248353 | 1.00 | RIPK1 (0.61) | RIPK1RORCABCB1GPR119MEN1 | |
| SCHEMBL7589379 | 0.88 | L3MBTL1 (0.51) | RIPK1RORCABCB1GPR119MEN1 | |
| SCHEMBL1274502 | 0.85 | RIPK1 (0.46) | RIPK1RORCABCB1GPR119MEN1 | |
| SCHEMBL8785800 | 0.84 | RIPK1 (0.47) | RIPK1RORCABCB1GPR119MEN1 | |
| SCHEMBL18448056 | 0.82 | RIPK1 (0.49) | RIPK1RORCABCB1GPR119NR1H2 | |
| SCHEMBL3188043 | 0.79 | NR1H2 (0.56) | RIPK1RORCABCB1GPR119NR1H2 | |
| SCHEMBL3188035 | 0.79 | NR1H2 (0.56) | RIPK1RORCABCB1GPR119NR1H2 | |
| SCHEMBL4870228 | 0.79 | ABCB1 (0.52) | RIPK1RORCABCB1GPR119NR1H2 | |
| SCHEMBL14074143 | 0.79 | ABCB1 (0.52) | RIPK1RORCABCB1GPR119NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2749553-A1 | Process for preparation of enantiomerically pure S-(+)-N, N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine | Deva Holding Anonim Sirketi (TR) | 2014-07-02 | — | — | EP | disclosed |